About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ1510235710615

Abstract : Background: Fat grafting is one of the common cosmetic procedures for soft tissue augmentation and plastic with reconstructive surgery. However, occasionally, non-tuberculous mycobacterium (NTM) species can be seen secondary to fat grafting. Objectives: To identify the infection risk of fat grafting technique by NTM, obtain an antibiogram of NTM isolates and treatment compliance with outcomes. Patients and Methods: In this study, 19 female patients who had received fat grafting for the face, breast, abdominal, buttocks and thigh for cosmetic purposes were reviewed. After being referred to our diagnostic centre, a specialized laboratory team collected specimens for detailed cultures and microscopic examination. Then, according to drug sensitivity results, targeted antibiotics were implemented for 9-24 months. Local proper wound and abscess debridement were conducted in some cases. On the other hand, repetitive acid-fast bacterium (AFB) smear examinations every 2-4 weeks were done for them. Results: The patients presented with local swelling and skin ulceration, many subcutaneous nodules, big lumps with fistula and abscess formation, and some with extensive skin ulceration. Patients received imperial narrow to broad-spectrum antimicrobial therapy, and the primary classical culture was inconclusive. Mycobacterium abscessus was the dominant invasive agent in most patients. After a one-year follow-up, all patients’ specimens were acid-fast smear-negative. Still, they experienced o

Paper ID : SMJ0910235710614
Sapporo Medical Journal
Author : Nur Fatimah Sirajuddin, Nusratuddin Abdullah, Suryani As'ad, Nasruddin AM,

Abstract : Objective: Perimenopause, or the menopausal transition, is a period when physiologic changes mark progression toward the end of the menstrual period. Physiological changes in perimenopause produce hormonal changes that manifest invariable symptoms that significantly affect a woman's quality of life, so complex clinical treatment is required. Ajwa dates (Phoenix dactylifera L.), one of the alternative treatments for perimenopausal women, have many benefits for reproductive function. The antioxidant and pro-apoptotic effects of ajwa dates are considered to improve the clinical features of perimenopause. Methods: This quasi-experimental study with a pre-post control design involved 44 perimenopausal women aged 42–48 years, which were divided into 2 groups randomly (28 subjects consumed 7 ajwa dates daily for 8 weeks as the intervention group, and 16 subjects did not consume any dates as the control group). Results: There were significant improvements in sleep disturbances, vaginal dryness, and mood changes in the intervention group compared to the control group (p<0.001, p < 0.001, and p = 0.002, respectively). There were no significant improvements in irregular menstrual cycles (p = 0.375) or vasomotor symptoms (p =0.063). Conclusion: Consumption of ajwa dates was effective in improving clinical features and perimenopausal women's quality of life.

Paper ID : SMJ2509235709613
Sapporo Medical Journal
Author : Lia Nurdini, Sabarinah Prasetyo, Legina Anggraeni, Muhammad Syukri,

Abstract : The determinants of unmet need for contraception vary between regions, so they have different influences for each location. Therefore, it is necessary to map cases and risk factors for unmet need for contraception in Indonesia based on the district/city level. This research aims to determine the determinants of the unmet need for contraception by considering spatial aspects. This research was carried out in 155 Muaro Jambi Regency, Indonesia and using secondary data for 2020 and 2021, with an analysis unit of 155 villages in Muaro Jambi Regency. This research uses an ecological study research design with analysis of Moran's index, Moran's scatterplot, and spatial regression SAR. This research was carried out from March to December 2022. There has been an increasing unmet need for contraception from 16.8% in 2020 to 20.6% in 2021. In addition, there is positive spatial autocorrelation between villages in Muaro Jambi Regency, seen from the p-value <0.05. Based on the results of spatial regression SAR, the variables that are significantly related in 2020 are the number of cadres (0.001), early marriage (0.022), and education level (0.00). Meanwhile, in 2021, education level has a significant influence, with a p-value of 0.000. This research is expected to provide a contribution in the form of information and input for central and regional governments in prioritizing intervention programs to reduce the unmet need for contraception at the district or city level.

Paper ID : SMJ1809235709611

Abstract : The high level of resistance to pathogenic bacteria causes the number of antibiotics to be limited. Therefore, searching for new antibiotics that can kill these resistant bacteria is necessary. A new approach to obtaining new metabolic products with various structures is "One Strain Many Compounds" (OSMAC). This strategy can offer a quick, easy, and efficient way to increase the diversity of secondary metabolites by enhancing and activating "silent biogenetic gene clusters." Through this research, the secondary metabolites of Penicillium simplicissimum Ch06 in a solid rice medium were compared to the same medium with the addition of 3.5% MSG and 3.5% NaNO3. The content of secondary metabolites was analyzed using LC-MS/MS method. The antibacterial activity of the fungus extracts was tested using the agar diffusion method. Adding MSG and NaNO3 to rice media affected the formation of secondary metabolites from the fungus. The antibacterial activity of fungal extracts induced by adding MSG and NaNO3 was greater than that of the control medium. The fungal metabolite profiles analyzed by liquid chromatography(LC)-mass spectrometry (MS) showed a clear difference of several peaks in the LC profile following the same trend with the variation of the antibacterial activity of the fungal extracts. Our results showed a clear difference in cultivation media with the addition of MSG / NaNO3 and fungal bioactivity.

Paper ID : SMJ1209235709609

Abstract : A worker is an individual who does work for life and is a social being who lives a family life [1]. Roles as workers and family members will experience conflict if not managed properly. When workers encounter a problem at work, it can negatively influence their lives and cause work-family conflict [2]. The contradictions between work and family happenings found by workers can also be the main reason for it [11]. This cross-sectional study determined the relationship between work type and family conflict. Work type and family conflicts were taken from the 2021 National Population and Family Planning Agency (BKKBN) in Tangerang Regency and South Tangerang City, where 1,048,573 data were obtained and spread across ten types of work, including those who are unemployed or serve both as heads of families and homemakers. Based on the results of the tests conducted, the relation result between the type of work and the incidence of family conflict were as follows: without greeting (for three consecutive days) p = 0.068, domestic violence p = 0.737, leaving the house/running away (for two consecutive days) p = 0.347, and separate beds between husband and wife (for seven consecutive days) p = 0.141. These data show no significant relation between work and the incidence of family conflict among the Tangerang population. However, the writer suggests researching more diverse types of family and work-family conflicts and covering all the problems that can arise in families.