Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : Introduction: Obesity is an increasingly growing universal health issue. Due to the prevalence of obesity and its association with an increased risk of cardiovascular disease requiring surgical intervention, it is important that the medical students have a good knowledge of these two correlated conditions. Aim: To assess the students' perception on the relationship between body mass index (BMI) classes and the outcomes of coronary artery bypass grafting (CABG) surgery among medical student in King Faisal University in Alahsa, Saudi Arabia. Method: This is a cross-sectional study, participants underwent An 11-item questionnaire that included three sections. The first section included questions about demographic data in the form of gender and study year, the second section included questions about CABG surgery complications e.g. renal failure and respiratory failure, and the last section investigated the relationship between BMI classes and CABG complications. Conclusion: CABG is a major procedure that is associated with many complications, Therefore, it is important to raise the level of awareness for both present and future doctors about this relationship in order to improve the overall patient care and the outcomes for these patients.
Abstract : The use of AMH level in predicting outcomes of in-vitro fertilization/intra cytoplasmic sperm injection in poor responder women has been widely used. Since the term “poor responder” of Bologna criteria has been changed to "low prognosis" according to the POSEIDON (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) criteria, which divided low prognosis into 4 groups, therefore these studies aim to evaluate serum AMH levels in the group suspected of low prognosis women treated with IVF/ICSI. A total of 252 patients of suspected low prognosis groups were assessed retrospectively between 2018 and 2019 in Morula Clinic, National Hospital, Surabaya, Indonesia. Serum AMH cut off values determined for low prognosis groups. Serum AMH levels and pregnancy rate were compared among 4 subgroups of suspected low prognosis women treated IVF/ICSI. In this study, the serum AMH cut off value for predicting low prognosis women using POSEIDON criteria was 1.7 ng/mL with sensitivity 86.7% and specificity 70%. The serum AMH levels were significantly difference in 4 subgroups of suspected low prognosis women treated IVF/ICSI (p<0.05). Interestingly, there were no differences in pregnancy rate among those groups. In conclusion, serum AMH level could predict low prognosis women treated IVF/ICSI. It is important to determine cut-off value to predict the low prognosis women. The pregnancy rate among low prognosis subgroups was not difference.
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Abstract : Burns causes vasodilatation resulting in increased capillary hydrostatic pressure which causes increased capillary membrane permeability. This causes fluids and electrolytes in the intravascular out to the extravascular including Albumin, resulting in hypoalbuminemia. Hypoalbuminemia is a condition in which the albumin level in the blood is below 3.5 g / dl. Based on the National Formulary according to the 2017 Minister of Health regarding restrictions on the provision of infusion albumin, patients are given human albumin transfusion if the albumin level is less than 2.5 g / dl. A solution is needed to increase albumin levels other than through transfusion, provided that this albumin transfusion alternative is expected to be more economical and efficient than transfusion albumin which is notoriously expensive. Channa striata extract is a new product which is expected to be an alternative to this transfusion albumin. The aim of the study was to determine whether the administration of Channa striata extract capsules can increase the albumin levels in the blood in burn cases. This research uses a systematical review method by taking journals through various databases. The conclusion of this study is that Channa striata extract capsules can increase albumin levels in the body and accelerate wound healing in burn patients. The research that also found Channa striata extract capsules also decreases serum MDA levels and increasing nitrogen balance in a positive direction
Abstract : Melasma is a pigmentation disorder with a multifactorial etiology. This condition is still a challenge for the field of cosmetic dermatology because it is recalcitrant to therapy and has a high risk of recurrence. Among the various risk factors known to play a role in the development of melasma, thyroid dysfunction is common to be found in this condition. This review attempts to gather evidence to quarry the relationship between melasma and thyroid hormone regulation disorders. The available evidence suggests that melasma can be influenced by inflammatory conditions, increased oxidative stress, and stimulation of Adrenocorticotropic hormone (ACTH) and Melanocyte-stimulating hormone (MSH) via the hypothalamic pituitary thyroid (HPT) axis in hyperthyroid conditions. By further understanding the pathophysiological conditions in this disorder, treatment and prevention of melasma progression can be carried out more effectively.