Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : The phytochemical analysis of different parts of Melia azedarach showed that the plant contained alkaloids, carbohydrates, fixed oil and fats, protein and amino acids, saponins, sterols, triterpenoids, esters, thiols, cynogenic glycosides, tannins, flavonoids and phenolic compounds. The pharmacological studies revealed that Melia azedarach possessed antimicrobial, antiparasitic, anticancer, antioxidant, antiinflammatory, analgesic, antipyretic, reproductive, hepatoprotective, dermatological, antidiabetic, immunological, antilithiatic, hypolipidemic, butyrylcholinesterase inhibitory activity and melanogenesis stimulation effects. The current review highlighted the constituents, pharmacological and toxicological effects of Melia azedarach.
Abstract : Vulnerable groups, such as pregnant women, are a group that is at risk of health problems during a disaster. Weak physical condition due to the impact of the disaster and high anxiety can cause contractions that can lead to miscarriage, premature birth, and labor that is earlier than it should be. Family involvement as community empowerment, so that the family as the smallest unit can recognize as early as possible the risks, disastrous impacts of pregnant women. This research consists of three stages. Stage 1 is an exploratory study. The second stage is model development. A Disaster Response Pregnant Mother Family Empowerment Model was developed and used to increase the ability to face disasters in the context of reducing the risk of pregnant women in disaster conditions. Family mentoring uses the empowerment model for disaster response families twice with a span of one week. The third stage of the research was a quasi-experiment with pre-post test two group designs. Samples per group are 20 people. The sampling technique was the purposive sampling technique. The pre-post test was conducted to determine knowledge and attitudes, using a questionnaire, while the skills used observation. In the control group, only modules were given. The research concludes that the family empowerment model for pregnant women who respond to disasters affects increasing the ability to reduce the impact of disasters.
Abstract : Background:Vitamin D is an essential factor for body healthy especially in pregnant, deficiency of this vitamin is worldwide distributed health careincluding Middle East. The aim of the study is a determine the relationships between vitamin D concentration and some social and hematological parameters in pregnant women in Thi-Qar province/South of Iraq. Method:A comparative analytical study design was used with in Bint Al-Huda public hospital- and Al-Rahman gynecology and obstetrics private hospital /Thi-Qar-Southern of Iraq. In a period from September to November/2020, list of questionnaire includings: age, occupation, residence, miscarriage and trimester. specific investigation involving complete blood count and vitamin D level assay were done by coulter counter and immune fluorescence technique.. Results: the result showed high prevalence of vitamin D insufficiency among the women under study with no significant differences among the group (p value = 0.887), and there are no significant relation between the age, occupation and residence with the vitamin D levels under (p value ≤ 0.05), while the results reveals significant differences in Hb, PCV and MCHC between groups under (p value = 0.014, 0.003, 0.045), respectively. Also, high level of correlation was seen between vitamin D concentration and hematologic parameters (Hb, PCV,MCHC) with significance correlation (p-value < 0.001). Conclusion:the high percent of women including pregnant in Iraq suffer from vitamin D deficiency and insufficiency and the socio-economic factor play a role in this status with the high correlation between vit. D level and Hb, PCV and MCHC levels of blood, diagnosis and treatment of vit. D deficiency with adequate 25(OH)D concentrations are critical to maintain a good health care for pregnant women. More studies are required to detects others factors related to this deficiency in Iraqi populations
Abstract : Percutaneous nephrolithotomy (PCNL) is frequently performed by Urologist as a main way of management of renal stones of large size. Fluoroscopy is used commonly to guide Percutaneous nephrolithotomy (PCNL) with the hazards of radiation to the patients and the operating team, that is why Ultrasound represents a good lower cost alternative to guide this procedure as it gives a better needle access, ensures urinary tract dilatation and localization of small residual radiolucent stones.Also; it has lesser risk of adjacent organs’ injuries. Patients and methods: In this prospective interventional study, one hundred ninety-three patients, aged 12 years and morewith staghorn renal stones of 70 millimeters diameter and less involved for the period of January 2012 till March 2019. All patients underwent necessary basic blood,urine and imaging studies for preoperative assessment. Patients divided into two groups based on the image guiding the operation, those who underwent Ultrasound guided Percutaneous nephrolithotomy (PCNL) were 115, and the rest 78 underwent Fluoroscopy guided Percutaneous nephrolithotomy (PCNL). Then, under general anesthesia; stone extraction performed with intraoperative assessment of operative time, total time of access, exposure time to radiation. And post-operative follow up of patients for complications and outcomes including stone free rate, any residual stone, need for ESWL or for second PCNL, failure of needle access, hospital stay, bleeding or hematuria, need for blood transfusion or embolization, fluid extravasation, fever or sepsis, Colonic or inferior vena cava injury, Pneumothorax or hemothorax. Results: The two groups were homogenous regarding gender and age, serum creatinine and hemoglobin concentration were not different between them pre-operatively. There was a higher stone free rate by using Ultrasonic guided percutaneous nephrolithotomy, and there was no statistical difference between the two procedures regarding the risk of injury to internal organs and bleeding, and both procedures did not cause colonic, hepatic or splenic injuries. Operative time, post-operative hospital stay and post-operative extravasation, fever, and sepsis were not significantly different between the two groups. Conclusion: Apart from stone free rate and radiation exposure, both ultrasonic- guided, and Fluoroscopy guided Percutaneous nephrolithotomy have the same value as surgical procedures for treatment of renal stones, and there was no significant difference between them.
Abstract : Background: Microalbuminuria is associated with an increased risk of cardiovascular events and death and chronic kidney disease in patients with diabetes mellitus and hypertension. epidemiologic studies have found that microalbuminuria is predictive, independently of other risk factors, for all-cause and cardiovascular mortality and CVD events within groups of patients with diabetes or hypertension, and in the general population Aim of study This study was designed to determine Correlation of microalbuminuria and Multiple Risk Factors in Acute Coronary Syndrome. Patients and methods The present study was carried out during period Oct 2019 to Jan 2020 on patients presenting to AL-Nassiriya Heart center and AL-Hussein Teaching hospital . It was an observational comparison study in which comparison of two groups according to the presence and absence of microalbuminuria in patient diagnosed to have acute coronary syndrome after proper history, thorough clinical examination and investigations and find their correlation with multiple risk factors for acute coronary syndrome Results and Discussion Microalbuminuria in cases population was found to be in total 34 patients out of 55(61.81%);whereas in control population, 3 patients comprising of 14.81 On comparison of these two populations, the difference between occurrence of microalbuminuria was found to be stastically significant(x2 =11.7 and p value 1 In MA+ve cases ,there were 4 cases with DM,3 cases of hypertension ,6 smokers and 13 with multiple risk factors. In MA-ve cases there were 2 cases of DM ,1 case with hypertension and 6 smokers and only 2 with multiple risk factors. The difference between occurrence of microalbuminuria was significant in cases with multiple risk factors ). In the present study the difference in occurrence of microalbuminuria were significant (p < 0.05)in acute coronary syndrome with multiple risk factors than isolated factor which is similar to DIABHYCAR and HOPE study Conclusions: This observation implies that microalbuminuria is significantly more commonly seen in patients with acute coronary syndrome as compared to healthy adults of same biological characteristics. The difference between occurrence of microalbuminuria was significant in cases with multiple risk factors than any isolated single risk factor