Sapporo Medical Journal

Abstract : This study aimed to determine the risk factors that affected the pulmonary function disorder of workers in the manufacturing industry. The research was observational with cross-sectional design, the population were 286 workers while the total sample were 150 workers in the production unit who have worked at least five years, and willing to become respondents. Data collected from interviews with workers and measurement of environmental parameters. Bivariate analysis used Chi-Square test and multivariate test using PLS-SEM (Partial Least Square- Structural Equation Modeling). The result of the bivariate showed that there were a significant correlation between the level of inhaled dust, the use of PPE, and nutritional status (p-value < 0.05 ) with pulmonary function disorder of workers and there are no correlation between total dust levels, gender, age, smoking habits, exercise habits, medical record, temperature, humidity, ventilation, and working period (p-value > 0,05). Multivariate test results (PLS-SEM) showed result of the dust exposure factors of 20.1%, physical environment of 11%, individual factors of 18%, and behavioral factors of 15.7% on pulmonary function disorder. The variable of workers pulmonary function disorder was affected by dust exposure, physical environmental factors, individual factors, and behavioral factors to 64,8%.

Abstract : The long-term use of plastic for food packaging affects monomer migration. Bioplastics can be used as an alternative for food packaging because bioplastics can reduce risks of health. This research aimed to determine the effect of glycerol and chitosan doses for the utilization of cassava peel waste as bioplastics food packaging and its effect on physical and microbiological food quality. This research is experiment with the independent variable of glycerol and chitosan doses as (3 % weight: 3 ml, 5 % weight: 5 ml and 7 % weight: 7 ml) and the dependent variables are the physical and microbiological quality of food. Sample at this research is Getuk, with 24 samples Getuk (100 gr/sample). The result of the research is total plate count of control as 11500 CFU/g, treatment group 1 at 8783 CFU/g, treatment group 2 at 6716 CFU/g, and treatment group 3 at 4400 CFU/g. Analysis of statistics used ANOVA test, the result showed significant differences in doses of glycerol and chitosan for organic waste utilization of cassava peels as bioplastics food packaging to physical and microbiological food quality with a p-value as = 0,000. The conclusion of this research is the addition of 7 % weight chitosan and 7 ml glycerol showed the optimal treatment to reduce the total plate count of food (getuk) and the organoleptic test showed the food (getuk) packaging with bioplastics quality is better than regular plastic packaging. It’s recommended to use bioplastics as food packaging because it's

Abstract : Otorhinolaryngological manifestations are among the clinical manifestations of COVID-19 infection. It’s crucial for the general population to have a holistic view about theses manifestations as a part of controlling pandemic. This study aimed to report the results of the perception and knowledge about COVID 19-related otorhinolaryngological symptoms in Saudi Arabia. This is a cross sectional anonymous questionnaire-based study that was carried in Saudi Arabia. The questionnaire included a variety of questions to evaluate public perception and knowledge about otorhinolaryngological manifestations due to COVID-19 infection. One thousand five hundred twenty-one responded to the questionnaire. Most of the participants have identified otorhinolaryngological clinical manifestations of due to COVID-19, dyspnea (85%), hyposmoa or anosmia (82%), dry cough (78%). Study participants were willing to call ministry of health hotline(MOH) in 74.6% when experiencing otorhinolaryngological manifestations during COVID-19. In addition,70% were convenient with self-isolation. However, most of them were cautious to visit the otorhinolaryngological clinics during the pandemic era. This study showed that Saudi people have sufficient knowledge about COVID-19 otorhinolaryngological manifestations. This reflects the success of MOH guidelines to control COVID 19 infection. Nevertheless, extra campaigns with special emphasis of otorhinolaryngological illness still needs to be implanted in a wider scale.

Abstract : The worldwide pandemic of Coronavirus disease 2019 emerged in December 2019 in Wuhan, China. Early identification of immunological biomarkers is a critical step for the disease diagnosis and progression in pursuance of classifying high-risk patients within the dearth of relevant information. Material and method In a retrospective study, the laboratory finding of 98 COVID19 positively diagnosed patients with ages ranged from 9 up to 77 years and administered to Prince Hamza Hospital, Amman, Jordan were used in the study. We have adopted the immunological parameters of WBCs, neutrophils, monocyte, basophils, D-dimer, CRP, and ESR as markers for anticipated diagnostic indicators. Results Laboratory findings of COVID-19 showed that total WBCs might not be affected with SARS-CoV-2 in the initial phase of the disease. While the lymphocyte, eosinophil, basophil and CRP gave a primary indication about the COVID-19 infection through lymphopenia, eosinopenia, basopenia and an increase in the CRP value. The results of total WBC give a highly significant positive correlation with neutrophils (p<0.05), negative correlation with eosinophil and ESR, and significant positive correlation with monocyte and CRP (p<0.05). The age of the patient gave a negative correlation with lymphocyte, a highly significant negative correlation with eosinophil (p<0.01), and a significant positive correlation with ESR and CRP (p<0.05). Furthermore, The ESR gave a significant positive correlation with age an

Abstract : Air is an environmental component needed for human survival. This means that the respiratory organs are constantly exposed to particles contained in the air, including harmful particles that interfere with health such as dust. As we know that the presence of dust in the industry. is something that is certain so that the dust must be controlled. On the other hand, the small scale industrial sawmill industry with thousands in number and spread in rural areas, this waste has not been utilized optimally. Sawdust can be used as a filter for air dust. The purpose of this study was to determine the effectiveness of various variations of wood sawdust in multiplex applications to reduce the level of Total Dust Particles. The type of research used is a quasi-experimental laboratory scale to be applied in the field. This study uses the Pretest-Posttest One Group design. Measurements were made using HVS with 24 study samples with 3 different thicknesses of 10 cm, 15 cm and 20 cm. The results showed a decrease in thickness of 10 cm by 2.31%, 15 cm by 4.01% and 20 cm by 9.08%. Statistical testing using the ANOVA test and obtained an alpha value of 0,000, it can be concluded that there is a relationship. Then it can be concluded that the most effective thickness is 20 cm.