Sapporo Medical Journal

Abstract : The phytochemical analysis of different parts of Melia azedarach showed that the plant contained alkaloids, carbohydrates, fixed oil and fats, protein and amino acids, saponins, sterols, triterpenoids, esters, thiols, cynogenic glycosides, tannins, flavonoids and phenolic compounds. The pharmacological studies revealed that Melia azedarach possessed antimicrobial, antiparasitic, anticancer, antioxidant, antiinflammatory, analgesic, antipyretic, reproductive, hepatoprotective, dermatological, antidiabetic, immunological, antilithiatic, hypolipidemic, butyrylcholinesterase inhibitory activity and melanogenesis stimulation effects. The current review highlighted the constituents, pharmacological and toxicological effects of Melia azedarach.