Sapporo Medical Journal

Abstract : Infected wounds are one of the most common health issues today, and there are numerous treatment options. These treatments, however, have drawbacks and are frequently expensive. We can produce a more effective, less expensive wound dressing for the treatment of infected wounds by employing chitosan or nano-chitosan alone or by combining each material with a pre-existing silver antibacterial like silver sulfadiazine. These findings demonstrate the combination of actives that inhibit and kill certain wound pathogens in a polymeric gel wound dressing after a series of antimicrobial efficacy tests in vitro and in vivo.