Sapporo Medical Journal

Abstract : Background: Subarachnoid hemorrhage (SAH) accounts for 50% of hemorrhagic strokes. Very few hemodynamic and biochemical parameters predict the severity, pattern, location, and therapeutic modalities for SAH. This study explores various parameters for predicting SAH. Material and methods: A retrospective study of 68 SAH patients admitted to Intensive Care Units (ICUs) of a tertiary care hospital. Patient details were obtained from medical records. Descriptive statistics were used to elaborate on patient-related details. Correlation analyses were used. The first correlation analysis determined the correlation between biochemical and hemodynamic variables with SAH severity, location, and pattern. The second correlation analysis correlated the selection of the treatment modalities and its associated outcomes in terms of SAH severity, location, and pattern. Results: The mean age of the participants was 47.84 years and 55.8% were males, indicating that most SAH cases occur in middle-aged males. Few biochemical or hematological parameters, other than creatinine and INR (r=1.25), can differentiate between healthy and SAH patients. However, some parameters, such as fibrinogen levels (r= -0.867), high systolic and diastolic blood pressure (r=0.28 and r=0.38), PT, PTT, and electrolyte levels mediate the pattern, location, and size of aneurysms. Conclusion: As per the findings of our study, parameters such as serum sodium, serum chloride, serum phosphate, INR, creatinine, systolic bloo