Abstract : Pressure ulcer is a condition often found in chronically ill patients with prolonged immobilization. Infected pressure sore can inhibit wound healing, wound treatment and worsen the patient's condition. Wound infections in hospitals are commonly related to nosocomial infection and antibiotics resistance. This research evaluated the incidence, bacterial growth pattern and antibiotics sensitivity of patients with pressure ulcer in Soetomo Hospital Surabaya. A total of 35 patients were admitted to RSDS and 14 patients fulfilled the requirements to be analyzed. We analyzed 14 patients’ medical records admitted to Soetomo Hospital from 1 October 2019 – 31 January 2020, including demographic data, diagnosis, decubitus site and stages, bacterial culture and antibiotic sensitivity. 71.5% of the patient were male and 57.1% categorized as old adult. Encephalopathy was the most common diagnosis found in pressure ulcer patients. A total of 85.7% of pressure ulcers were developed in the sacral region. Out of 19 isolates, the most common bacteria found is E.coli, followed by E. faecalis, P. aeruginosa, and A. baumanii. Amikacin demonstrated a high sensitivity against the majority of gram-negative bacteria. E. coli were very sensitive to amikacin, imipenem and meropenem. Cefepime, ceftazidime, gentamycin, imipenem, and piperacillin-tazobactam were other antibiotics that showed 100% sensitivity to P.aeruginosa. Cefoperazone-Sulbactam was the only antibiotic very sensitive to A. baumanii.