Abstract : Background: Hypercholesterolemia is one of the major risk factors for coronary heart disease (CHD) that takes the most lives in the world today. This study aims to develop a nutritional model that is effective for hypercholesterolemia patients in maintaining a normocholesterolemic condition after receiving short-term anti-hypercholesterolemia drug therapy. Methods: This research was a descriptive study with cross-sectional design. A descriptive survey was carried out in the community regarding the menu of hypercholesterolemia patients as a risk factor for hypercholesterolemia in Palembang along with a literature review to build a Theoretical Model, then continued with Nominal Focus Group Discussions and then carried out the construction of an Operational Model, namely nutritional pattern management involving nutritionists. The samples in this study were 374 residents in Palembang City. The sampling technique was purposive sampling. Data analysis in this study was carried out descriptively and analytically using the Chi-square test. Results: There was a significant difference between the cholesterol level category and the diet in the form of menu categories, food processing methods and daily total calories (p value = 0.000) p <α. Conclusion: There is a significant association between cholesterol levels and dietary patterns, food processing methods and total calories per (p value = 0.000) p<α.