Abstract : A prospective study that include ( 100 ) patients who underwent emergency laparotomy for perforated duodenal ulcer during a period from May 2016 to January 2018. The operations were done in Al-Husein Teaching Hospital. The clinical finding, general risk factors, co-morbid medical diseases, operative finding, and post – operative complications were all taken in consideration. Follow-up period range from 2 weeks to 18 months. in this study,( 96%) male and( 4%) female with mean age of 43.13 years (range from 10 to more than 70) years. The disease was more common in rural areas (58%) than in urban areas (42%). Fifty five percent of patients gave previous history of duodenal ulcer and ( 45%) had no previous history of duodenal ulcer. The most common risk factors are smoking ( 32% ) and NSIADs (25%) . In this study most of elderly patients presented with medical diseases as hypertension, diabetes mellitus, ischemic heart disease, and chronic obstructive pulmonary disease. Most patients admitted to hospital between 19 – 24 hours ( 21%), ( 8%) admitted during 6 hours, and ( 2%) admitted after (120) hours. Regarding the complications occur in this study; wound infections, chest infections, and paralytic ileus were the most common complications. Mortality rate occur in 2%. The most common factor that leading to development of postoperative complications is delayed in hospital admission, so, to improve the results of treatment of perforated duodenal ulcer, the diagnosis and treatme