Abstract : Introduction: Telogen effluvium is a temporary form of excessive hair shedding, and it can occur due to a variety of physical or mental stressors. This study aimed to observe the relationship between hair loss and anxiety among male and female in Poly Clinic at King Faisal University, Saudi Arabia. Methods and Material: This is a cross-sectional study conducted in Polyclinic at King Faisal University. A well-structured questionnaire was distributed among males and females. Results: The prevalence of hair loss associated with anxiety was 21.7% (n=82). The most frequently mentioned reason for hair loss was lack of vitamins (26.2%), followed by psychosocial disorder (18%). In univariate analysis, nationality, history of the stressful event, having recurrent, irresistible urges to pull out hair from the scalp and taking medication were all significantly influenced hair loss associated with anxiety. In the multivariate regression model, history of the stressful event, used of Minoxidil hair spray and those who seek treatment for anxiety were the significant independent factors associated with anxiety. Conclusions: Hair loss associated with anxiety were minimal. Stress used Minoxidil spray and seeking treatment for anxiety likely to be the reason for hair loss associated with anxiety. Meanwhile, lack of vitamins, psychosocial factors and hereditary influence branded as the reason for hair loss.