Abstract : In Saudi Arabia, colorectal carcinoma is the second most common type of cancer. According to the Saudi Health Council, 1,659 colorectal cancer cases were diagnosed in Saudi nationals in 2016, accounting for 12.6% of all newly diagnosed colorectal cancer (CRC). This study aimed to detect colorectal cancer in Saudi patients by determining the diagnostic accuracy of contrast enhanced computed tomography (CECT). This retrospective study was conducted in King Fahad medical city, computed tomography (CT) department during the period from February to May 2019. 54 patients were scanned using a convenience sampling technique, contrast-enhanced CT was performed, Sensitivity and Specificity of (CECT) were calculated to evaluate detection of colorectal cancer. A social science statistical package (SPSS) was used to analyze the data .The study found that there were 54 patients with colorectal cancer, 57.4% were males, while 42.6% were females. . The patients' average age was 54.28±13.171 years. Contrast enhanced computed tomography demonstrated an 87% accuracy of diagnosis, with a sensitivity of 89.36% and a specificity of 50% (P<05). The study concluded that CECT (contrast enhanced computed tomography) is a non-invasive imaging modality that used to diagnose and differentiate colorectal lesions., with a sensitivity of 89.36% and a specificity of 50%.