Abstract : The pattern of food consumption and a wrong lifestyle can spur the emergence of oxidative stress, especially in adult humans. Oxidative stress can be inhibited by consuming foods that contain high antioxidants. Red dragon fruit contains a high source of antioxidants. This study aims to analyze the effectiveness of red dragon fruit (Hylocereus costaricensis) as a functional food in maintaining lipid profile levels under normal conditions (prevention of dyslipidemia) in adults. This study is a clinical experimental study with a pre and posts randomized controlled group design. This research used a quantitative analytic research type with an experimental study approach, using the RCT (Randomized Controlled Trial) method. The sample was taken by purposive sampling with a simple random sampling method. The intervention group was given red dragon fruit in 180 grams/day for 15 days. Levels of blood lipid profiles were measured before and after treatment. Data were analyzed by the Kolmogorov-Smirnov test for data normality test. Paired t-test to determine the difference in mean pretest and post-test in one group after treatment. Independent t-test to determine differences in the mean difference between pretest and post-test between groups given different treatments and nutritional intake from food due to 24 hours of food recall was analyzed using the Nutrisurvey program.