Author : Wael Abu Dayyih, Mohammad Hailat, Omar Al-Asasfeh, Hala H. Alhunaity, Thabet H. Althneibat,

Abstract : The consumption of herbal beverages, such as pomegranate juice (PJ), has experienced a notable surge in recent years. The concomitant utilization of prescription medications and herbal products is prevalent, which may have implications on therapeutic outcomes and adverse effects. Numerous studies have demonstrated that different juices can alter enzymes and transporters that regulate pharmacokinetic parameters, leading to clinically significant and unpredictable effects. Despite being extensively studied for its medicinal properties and potential health benefits, the interactions of pomegranate (Punica granatum) with conventional medications are still under investigation. This fruit, which has a long history of traditional medicinal use for various therapeutic purposes, is widely consumed globally. Pomegranate comprises a diverse range of chemical constituents that include sugars, organic acids, polyphenols, fatty acids, anthocyanins, flavonoids, alkaloids, sterols, triterpenes, and vitamins. These constituents can vary based on factors like agricultural practices, geographical region, fruit ripeness, and storage conditions. The polyphenolic compounds found in pomegranate, such as tannins and flavonoids, are particularly rich and possess potent anti-inflammatory, antioxidant, antibacterial, antidiabetic, cardioprotective, and anticarcinogenic properties. Due to the multifaceted therapeutic properties and extensive chemical composition of pomegranate, researchers have been in

Volume and Issue
Full Article Download