Abstract : Purpose: To identify various perioperative factors that could affect early mortality in Tetralogy of Fallot (TF) patients after the total correction procedure. Method: This retrospective cohort study used a cross-sectional design using secondary data from medical records of TF patients who underwent total correction procedures at Dr. Soetomo Academic General Hospital, Surabaya, Indonesia from August to September 2019. The study outcomes were a single risk factor or concomitant risk factor that affected the mortality rate during post-total correction treatment of TF patients. Results: Forty-two patients undergoing total repair surgery during the study period, this study had a mortality rate of 33.3% (14 patients). Univariate analysis reveals factors influencing mortality namely age <24 months (OR=15.0, p=0.02), weight <10 kgs (OR=6.25, p=0.025), SaO2 <75% (OR=12.833, p=0.013), HCT >65% (OR=4.5, p=0.049), ventilator time >48 hours (OR=4.5, p=0.031), Fever (OR=50, p=<0.001), residual PS (OR=14, p=0.021), residual VSD (OR=16.1, p=0.003), VIS (OR=59.8, p=<0.001). Conclusion: In our study, we found variables that influenced mortality rate in univariate analysis. A cardiac surgeon can take this into contemplation while choosing the best option for the patient by seeing these perioperative factors to reduce the mortality rate in TF cases after total repair. Keywords: Mortality rate, Perioperative Factors, Tetralogy of Fallot, Total Correction

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