Author : Indranila Kustarini Samsuria, Anggie, Judiono, Purwanto Adhipireno,

Abstract : Chronic kidney disease (CKD) is a public health problem, as its prevalence continues to increase the incidence of kidney failure, poor prognosis, and high treatment costs from year to year. Reduction function and the number of nephrons caused kidney dysfunction, so a buildup of substances that are not needed by the body and electrolyte disturbances appears. The study aimed to determine the relationship between serum sodium and potassium electrolyte levels in patients suffering from chronic kidney disease (CKD). Analytic observational research by cross-sectional design was applied. The study was conducted on 30 patients with chronic kidney disease in RSUP Dr. Kariadi Semarang. Data collected were conducted by Na and K electrolytes, and they were analyzed by the Iodine Deficiency Disorders (GAKI) laboratory in the January-March 2020. Data were analyzed and presented on average ± SE, correlation statistics, Pearson and Spearman regression with significance levels of p <0.05. The Research Ethics Commission approved this study. The results showed was not significant a correlation of potassium (K) with age (p = 0.405; r = 0.158). Potassium and ureum was significantly the relationship positive (p = 0.003; r = 0.522). The relationship between potassium and creatinine was significantly positive (p = 0.024; r = 0.412). Conclusion there was a significant serum K relationship with urea and creatinine

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