About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ2809215509384

Abstract : The aim of the study was to elucidate a plausible predictive value of the macrophage migration inhibitory factor (MIF) levels for one-year clinical outcomes in ST-segment elevation myocardial infarction (STEMI) patients underwent primary percutaneous coronary intervention (PCI). Materials and methods: 134 STEMI patients underwent PCI were enrolled in the study. The MIF levels were determined at baseline, directly prior and after PCI along with conventional observations. Results. During 1-year follow-up 37% of patients has reached the composite endpoint (all-cause mortality, non-fatal STEMI, and non-fatal stroke, hospitalization for unstable angina, heart failure decompensation, and PCI). We have found that pre-PCI MIF levels > 3934 pg/mL might be an independent predictor of composite endpoints with sensitivity 54% and specificity 82%. Positive correlation between MIF and inflammatory biomarkers was revealed. Adverse outcomes associated with higher pre- and post-PCI MIF levels (OR 1.0, 95% CI 1.0001–1.0008; p=0.013 and OR 1.0, 95% CI 1.0001–1.0009; p=0.019) and CRP that determined during the first week after the event (OR 1.0, 95% CI 1.005–1.2, p=0.03). Kaplan-Meier analysis has shown substantially lower long-term survival rate in patients with the MIF level > 3493 pg/ml when compared with the MIF level ≤ 3493 pg/ml. Conclusions: The MIF levels exceeded 3934 ng/ml were associated with the higher risk of one-year adverse clinical outcome in STEMI patients underwent primary PCI

Paper ID : SMJ2709215509382

Abstract : This study determines the prevalence and socio-demographic of HIV among tuberculosis patients and intravenous drug users (IDUs) in Hospital Universiti Sains Malaysia (HUSM), Kubang Kerian, Kelantan Malaysia. All the data collected was entered in MS Excel Database. Thereafter data entry and analysis were conducted using Statistical Packages for Social Sciences (SPSS) version 26. The continuous variables were expressed as mean (SD) and categorical variables were expressed as frequencies and percentages. The result showed that The mean age of HIV among tuberculosis patients was 33 years old. Most of the patients were male (82%), Malay (90%), non-Malay patients is 10% only, half of all HIV among TB patients have a low CD4 count of fewer than 200 cells/mm3, 24 percent of HIV cases are reported due to heterosexual, 3% of HIV among TB patients were infected through blood transfusions and most patients were smoker (65%). In conclusion, as the prevalence of TB/HIV coinfection is associated with the prevalence of HIV in the general population, and antiretroviral therapy is effective in treating both diseases, HIV-infected patients should begin treatment as soon as possible.

Paper ID : SMJ2309215509380
Sapporo Medical Journal
Author : Lisa Trina Arlym, Endang L. Achadi, Dwiana Ocviyanti,

Abstract : Globally, low birth weight (LBW) is still being a maternal public health problem. LBW is caused by various factors, which affect shorter gestation period, fetal growth restriction or both. Adequate frequency and quality of antenatal care (ANC) visits are recommended to identify problem as early as possible and to monitor the health of the mother and baby. ANC has been proofed as determinant to reduce the incidence of LBW. This study aims to identify whether adequate frequency and quality of ANC visits decrease the incidence of LBW in developing countries. The research was using systematic literature review which performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All references are managed using Mendeley software, then found 14 selected articles that meet the inclusion criteria and have high quality assessed by using critical appraisal tool from Centre for Evidence-Based Medicine (CEBM). The studies showed there were significant association between adequate frequency of ANC visits with the incidence of LBW. Other factors associated with LBW were socio-demographic factors and maternal factors. Frequency of ANC at least 4 times during pregnancy can still give positive effect towards low birthweight risk, however, it should be a quality service of ANC. Keywords— LBW, ANC, antenatal care, pregnancy, pregnant women

Paper ID : SMJ1809215509379
Sapporo Medical Journal
Author : Aisha Alghamdi, Ameen Mohammed Abdulwahed, Abdullah Mohammed AlShaibi, Faisal Ahmed Bawazir, Omar Adnan Youldash, Majed Abdulkarim Filimban, Mohammed Khalid Sulaimani,

Abstract : Type 2 diabetes mellitus (T2DM) is a noncommunicable illness that develops due to insulin resistance and persistent hyperglycemia. People older than 65 years have a higher chance for getting diabetes. We aimed to measure the quality of life (QoL) among the elderly type 2 diabetic population in Makkah region. A cross-sectional study was done in older adults in Makkah. We included all participants older than 65 years who were diagnosed with T2DM. World Health Organization Quality of Life Brief Version (WHOQOL-BREF) scale was used to measure the QoL among patients with diabetes. Data were analyzed using SPSS statistical program version 25. A total of 399 participants were included. Most participants were between 65 and 70 (65.7%) and 71–75 (23.3%) years. Two hundred and twenty-two (55.6) of them were male. The mean WHOQOL-BREF scale score was 14.83 ± 2.79, and a significant negative correlation was found between WHOQOL-BREF scale scores and participants’ age (r = −0.16, p-value = 0.001) and positive correlation with participants’ educational level (r = 0.275, p-value ≤ 0.001). The overall QoL was high among elderly patients with diabetes. Educational level and age were also correlated with a higher QoL. We should concentrate on increasing the level of education among elderly patients with diabetes to increase their QoL.

Paper ID : SMJ1709215509378

Abstract : Chronic hypertension in pregnancy, gestational hypertension, and hypertension in preeclampsia are uniquely challenging conditions for pregnant mothers, because the pathology and treatment methods affect both the mother and the fetus and sometimes cause contradictory health outcomes. Preeclampsia is one of the most worrying complications, especially in pregnancy. Preeclampsia often manifests as new-onset hypertension and proteinuria in the third trimester, which can quickly develop into serious complications, including the death of the mother and fetus.A 35-year-old woman was admitted to the hospital due to menelipsis for 33+5 weeks and was found to have abnormal blood pressure for 5+ months. According to blood pressure measurements and urine protein +- and the condition of placenta, she was hospitalized for pregnancy with chronic hypertension and early-onset preeclampsia. The result of the placental growth factor test was 30.63. A caesarean section was recommended to extract the fetus quickly to avoid the potential harm caused by severe eclampsia. The patient’s blood pressure during the operation was high, which was characteristic of severe eclampsia. Therefore, an emergency caesarean section was performed to ensure the safety of the patient and the fetus. Postoperative eclampsia symptoms disappeared and the placental growth factor index was normal. The patient's postoperative clinical course was smooth and satisfactory.