Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : Osteoarthritis is the single most common cause of disability in older adults. A study reported that musculoskeletal disorders were much greater than previously thought and accounted for 6.8% of the factors contributing to decreased age productivity in patients worldwide. This study is a retrospective analytic observational study with a cross sectional approach to postoperative high tibial osteotomy (HTO) patients at Dr. Soetomo general hospital and Husada Utama hospital in Surabaya. It was found that the most gender data were women with 20 patients (86.9), the most age was 51-60 years with 12 patients (52.1%), the most BMI was obese with 11 patients (61.1%), and the KOOS score of the pain, symptoms, activity daily living, sports, and quality of life components are 89.29, 92.51, 93.61, 56.96, and 82.61. Based on the FTA angle, the most patients were varus 4 and valgus 6. In addition, there were a significant difference between the mean FTA angle and between VAS average before and after surgery (p=0.000) and (p=0.000). There is an improvement in terms of clinical, radiological, and satisfactory KOOS score
Abstract : Background: Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder in women of reproductive age with a prevalence of up to 10%. Aim: The aim of this study was to evaluate vitamin D levels in PCOS women compared to normal fertile women and the relation between vitamin D and fasting insulin hormone levels in PCOS women. Materials and Methods: A prospective case-control study was conducted on 80 subjects who were classified into two groups: group (I) cases included 40 infertile women diagnosed with PCOS and group (II) control included 40 normal fertile women. Demographic and clinical characteristics of all the patients were recorded Results: No significant differences were noticed between groups regarding age, body mass index, sun exposure, however, cases group had lower gravidity. The results showed that LH level was significantly higher in PCOS group compared to the control one, while the opposite trend was observed in FSH levels. The fasting insulin hormone level was higher in PCOS group compared to control. PCOS group had a significantly lower 25 (OH) D level in comparison with the control group. In the PCOS group, 25 (OH) D level was negatively correlated with both fasting insulin level and body mass index. Conclusion: Women with PCOS had a significantly lower serum 25 (OH) D level compared to normal fertile women. Insulin resistance was prevalent in PCOS patients and there was a significant inverse correlation between vitamin D level and both fasting ins
Abstract : Background : COVID 19 pandemic result in great thread to the public health and by the measures taken to limit viral transmission , a lot of maternal healthcare services had been disrupted .Our research aimed to assess the impact of COVID-19 on access to maternal health services in Basrah city .method : This is a descriptive retrospective records based study implemented during the period from 1st of March 2019 to 31st of August 2019 (pre-COVID19 ) compared to same months of 2020 (intra-COVID 19). All pregnant women who attended to six chosen primary health care centers in Basrah were included in the study. Results: Comparing 2019 maternal health services indicators with those from 2020, there is reduction about 22% in women in first antenatal visits and 33% in antenatal visits more than one less than four ,49% in visits equal and more than four , postnatal visits by 16% and tetanus toxoid doses by 17% . The greatest reduction occurred in March 2020 then these services utilization surged in July 2020 and decreased again in August .Conclusion:Our results demonstrate negative effects of COVID-19 on maternal health access and a deficient health information system in Basrah.
Abstract : Unprovoked epilepsy is a common chronic brain disorder but the exact pathogenesis of is not clearly understood. Recent studies demonstrated the possibility for the transient receptor potential vanilloid type 1 (TRPV1) to be involved in this neurological illness and the molecular targets of most of antiepileptic medications are ion channels such as transient receptor potential (TRP) channels, which are thought to be partially responsible for epileptic seizures. To determine if there is any correlation between electroencephalogram changes in adult patients with unprovoked epilepsy disorder and (TRPV1) protein concentration. A case-control study was conducted on a total of 154 (male and female) subjects, 76 of them constituting the case group, which presented with unprovoked epilepsy, and the other 78 of making up the control group. The study data were collected during the period from 15th September 2020 to 1st July 2021 by the use of routine electroencephalogram with activation procedure and assessment of protein level by the sandwich ELISA method, in addition to other biochemical and haematological investigations. The mean TRPV1 protein concentration was (0.53 ± 0.8) in epileptic patient, and the highest mean protein concentration was among patients aged >45 years, with no significant differences between the case and control groups. A significantly higher mean TRPV1 concentration was associated with a positive family history of epilepsy, and the absence of epileptiform changes
Abstract : This study aimed to demonstrate the effect of Helicobacter pylori (H. pylori) infection on spirometric parameters and to highlight the prevalence of H. pylori infection in patients with chronic obstructive pulmonary diseases (COPD) as well as to study the association between H. pylori infection and severity of COPD. One hundred and fifty adult COPD patients aged 20-75 years of both genders were included in the study, patients were divided into two groups; the first group (cases) included 60 H. pylori positive COPD patients, the second group (control) included 90 H. pylori negative COPD patients. Assessment of pulmonary function by measurement of spirometric parameters and detection of H. pylori infection by stool rapid antigen test were done to all patients in both groups. Patients in both groups were comparable with regard to demographic characters. Moreover, the predicted values of forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC, peak expiratory flow rate (PEF) and forced expiratory flow rate in mid expiration (FEF25-75) were not significantly different between the two groups (P0.05). A significantly lower FEV1, FEV1%, FVC and FVC%, FEV1/FVC, PEF, PEF%, FEF25-75 and FEF25-75% were noticed in case group compared with control group (P0.05). While, FEV1/FVC % was not significantly different between the two groups (P0.05). The severity of air way obstruction and cough symptom was significantly more in case group compared with control grou