About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ0501245801634
Sapporo Medical Journal
Author : Wael Abu Dayyih, Mohammad Hailat, Omar Al-Asasfeh, Hala H. Alhunaity, Thabet H. Althneibat,

Abstract : The consumption of herbal beverages, such as pomegranate juice (PJ), has experienced a notable surge in recent years. The concomitant utilization of prescription medications and herbal products is prevalent, which may have implications on therapeutic outcomes and adverse effects. Numerous studies have demonstrated that different juices can alter enzymes and transporters that regulate pharmacokinetic parameters, leading to clinically significant and unpredictable effects. Despite being extensively studied for its medicinal properties and potential health benefits, the interactions of pomegranate (Punica granatum) with conventional medications are still under investigation. This fruit, which has a long history of traditional medicinal use for various therapeutic purposes, is widely consumed globally. Pomegranate comprises a diverse range of chemical constituents that include sugars, organic acids, polyphenols, fatty acids, anthocyanins, flavonoids, alkaloids, sterols, triterpenes, and vitamins. These constituents can vary based on factors like agricultural practices, geographical region, fruit ripeness, and storage conditions. The polyphenolic compounds found in pomegranate, such as tannins and flavonoids, are particularly rich and possess potent anti-inflammatory, antioxidant, antibacterial, antidiabetic, cardioprotective, and anticarcinogenic properties. Due to the multifaceted therapeutic properties and extensive chemical composition of pomegranate, researchers have been in

Paper ID : SMJ2612235712630
Sapporo Medical Journal
Author : Atiya Kareem Mohammed, Mahabat Hassan Saeed,

Abstract : Background: The ovarian reserve needs to be identified to diagnose and treat infertility. Methods and Material: descriptive, retrospective observational research. 230 people were included in the data from the roughly 500 patients who met the inclusion criteria and were admitted to the Sulaymaniyah Governorate's Royal Hospital (Infertility Center). The data were utilized to compare the robust regression model with the quantile regression model in medical data using statistical methods (SPSS24, Minitab19 and Eviews 10). The P-value and the Chi-Square test are performed to evaluate any significant correlations between variables. P-values less than 0.05 are considered significant. Results: The vast majority, 34.7% of those women older than 30, had fewer than 8 eggs, while 39.7% had between 8 and 15 eggs. There is a statistically significant relationship between (Age, TSH, FSH and PL) with the number of eggs because the p-value of these was less than the common alpha of 0.01. On the other hand, there is no statistical significance between LH and P4 on the number of eggs because the p-value of both variables was more than 0.05. Conclusion: The study concluded that the number of eggs was affected by age, follicle stimulation hormone, and thyroid stimulating hormone. However, no relation between the number of eggs and the luteinizing and progesterone hormones could be found.

Paper ID : SMJ2012235712629
Sapporo Medical Journal
Author : Erlin Syahril, Nusratuddin Abdullah, Muhammad Ilyas, Suryani As'ad, Lina Chorida, Rosdiana Natzir, Liong Boy Kurniawan, Burhanuddin Bahar, Nasrudin A. Mappaware,

Abstract : Objective: Perimenopause is the transition from the reproductive period to the menopausal stage with decreased number and function of oocytes. Transvaginal ultrasound is a reliable alternative method of detecting ovarian reserve. Ajwa dates contain complex macro and micronutrient components complemented by phenolic and flavonoid content considered potential to improve the condition of the ovaries of perimenopausal women which can be assessed through transvaginal ultrasound. Methods: This research is a quasi-experimental study with a pre-post control design carried out at RSIA Sitti Khadijah I Muhammadiyah Makassar, South Sulawesi, Indonesia, in February-August 2023. The study involved 44 perimenopausal subjects aged 42-48 years who were divided into 2 groups randomly (28 intervention groups, 16 control groups). Comparison of ovarian follicular changes analyzed with the Mann-Whitney U test. Result: The results of this study showed a decrease in the number of ovarian follicles with an increase in follicle size in the intervention group compared to the control group which experienced an increase in follicle count and a decrease in follicle size in the control group that was statistically significantly different (p< 0.05). Conclusion: Consumption of ajwa dates as an exogenous antioxidant can affect the number and size of antral follicles which is one of the predictive indicators of menopause.

Paper ID : SMJ0412235712628

Abstract : Malaria infection is still a public health concern in Batubara District, North Sumatera, Indonesia. Spatial clusters and hotspots of malaria cases are needed to help design elimination strategies in the district. Astudy was undertaken to detect clusters and hotspot of malaria during 2018-2020 in the district. All malaria cases’ house geo-coordinate were captured by using GPS. A retrospective space-time scan statistics analysis based on population data and annual malaria incidence was performed using SaTScan. The Poisson model was employed to determine the high risk of malaria and the highest of likelihood ratio (LLR) stated as most likely cluster, with the significance level of 0.05. There were 1,229 malaria cases reported in Batubara District and the annualized average incidence was 2.73 per 1,000 population. The SaTScan analysis identified three most like clusters and three secondary clusters, while Morans’I showed that there was spatial autocorrelation of malaria in the district. The sub-district of Tanjung Tiram, Sei Suka, and Talawi were consistently the location of clusters. There is evidence for the existence of statistically significant malaria clusters in Batubara District, North Sumatera, Indonesia. These findings may assist health authorities to improve the malaria preventive strategies and develop public health interventions, with special reference to the areas where the clusters and hotspots were found to achieve the malaria elimination goal.

Paper ID : SMJ1911235711625
Sapporo Medical Journal
Author : Yasser Abdelghani, Mostafa Ryan, Mostafa Aboelala, Sharehan Abdel rahman, Omar Abdelazim,

Abstract : Background: Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic fatty pancreatic disease (NAFPD) are expected to increase because of the rising prevalence of central obesity. Aim: to study weight reduction effects on metabolic, anthropometric, and ultrasound parameters in non-diabetic, overweight, and obese people with NAFLD and NAFPD. Subjects and methods: 133 adults aged 35-65 who were obese or overweight and had no diabetes participated in this study for six months. Participants underwent an individualized, intensive lifestyle program that included dietary changes. The diet recommendation was a low-fat hypocaloric meal. All subjects underwent ultrasound (US) examinations before the program, at 3rd month as well as at 6 months. We assessed the effects of weight loss on NAFPD (at baseline, 3 months, and 6 months) by linear mixed components. Result: Triglycerides and transaminases, two laboratory parameters, were significantly reduced by the ending of the study. The ultrasound outcomes revealed that in non-diabetic people who are overweight or obese, losing weight significantly lowers NAFLD while leaving NAFPD unaffected. No association was found between NAFPD and anthropometric parameters, blood pressure assessments, or blood indicators at rho > 0.4. Conclusion: weight reduction leads to a substantial drop in NAFLD in overweight and obese non-diabetics. Losing weight, on the other hand, seems not to affect the NAFPD.