Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : Background: Colorectal cancer constituting one of the most frequently occurring malignancies.Previous studies exhibiting the cells of the host signaling manipulation by the bacteria, where chronic or carriage of the bacterial infection can triggering the cancer development among the predisposed genetically persons. Justification: Usage of such triage link can solve many probabilities in studying the role of bacterial risk in cancer. Aims: Studying the Triage of Colorectal Cancer ,Lymphocytic Cell Infiltration , And Bacterial Infection Method: A 76 cases compared with nearly similar number of control by selecting their histopathologic specimens most of the control where excluded because of the insufficient sample size.Comparison done in Thi-Qar province- Southern of Iraq, extended from September 2020 the end of June 2021. Bacterial DNA was detected by PCR technique, and the PCR results were linked with demographic parameters such as age and gender. The data were examined by SPSS (26), P value <0.05consider significant. Result: Universal bacterial primer gave a positive results in 58(57.4%) of cases and only 8 (7.8%) cases of this where positive for bacterial primers. Most cases of colorectal cancer grade were grade II -A 36.8% followed by grade II-B 19.7%. The distribution of bacterial DNA universal primer was highly amounted in Stage III (56.8%) followed by Stage II, and the bacterial DNA were also detected in higher proportion in stage III of colorectal cancer followed by
Abstract : Conjoined twins are a rare case. Thoraco-omphalopagus was one of the most common types of conjoined twins. The management of thoracic defects presents a great challenge, especially since no standard procedures for chest reconstructions are available in the center. In this case report, we describe the successful reconstruction of a thoracic defect in thoraco-omphalopagus 17 months years old conjoined twin with titanium mini-plate and wire stabilization. The twins are now 2.5 years old, are healthy and have normal growth, and are under follow-up.
Abstract : Transurethral resection of the prostate (TURP) is currently the gold standard procedure for benign prostate hyperplasia (BPH). It may lead to various complications, such as urinary tract infection (UTI). Antibiotic prophylaxis use for TURP in the world has been studied, especially in the high-risk case. We aimed to evaluate the effectiveness of antibiotic prophylaxis in reducing bacteriuria and sepsis incidences on post-TURP patients. A systematic search was conducted in PUBMED, SCIENCE-DIRECT databases. The eligible analysis and article selection followed The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) protocol, analysis of bias used Cochrane Risk of Bias Tools, each was done by 2 independent reviewers. Five RCT articles are declared eligible and involved 872 patients. Forest plot shows data heterogeneity from post-TURP bacteriuria incidence, and there is significant difference between antibiotic prophylaxis and placebo/no therapy (OR=0.38, 95% CI=0.17 – 0.88; p = 0.02). The Forest plot shows data homogeneity from post-TURP sepsis incidence, and there is no significant difference between antibiotic prophylaxis and placebo/no therapy (OR=0.64, 95% CI=0.09 – 4.53; p = 0.66). Post-TURP bacteriuria incidence in patients administered with antibiotic prophylaxis is lower than placebo/no therapy, but post-TURP sepsis incidence in patients administered with antibiotic prophylaxis is the same as placebo/no therapy.
Abstract : Heart failure (HF) remains a leading cause of mortality in patients with overt cardiovascular disease (CVD). New Universal Definition and Classification of HF is supposed to use biomarker strategy based on measure of circulating (mainly natriuretic peptides and high-sensitive cardiac troponins) and genetic indicators to identify patients at higher risk of HF and choose optimal strategy to diagnose and treat. Although the first-generation biomarkers (natriuretic peptides, high sensitive cardiac troponins) are widely used, the second-generation biomarkers of fibrosis and inflammation may have additional promising benefit in clear assessment of adverse cardiac remodeling and providing differentiation between several subtypes of HF. Growth differential factor-15 (GDF15) is a stress-induced multifactorial cytokine, which belong to the transforming growth factor beta superfamily. GDF15 is markedly expressed in various cells and involved in glucose and energy homoeostasis, regulation of appetite, and body weight loss. GDF15 influences tissue protection from ischemia / reperfusion, and oxidative stress damage. The aim of the narrative review is to elucidate the diagnostic and therapeutic role of GDF15 in HF. We found that GDF-15 is a promising indicator of poor clinical outcomes and predictor of HF, and it could be a powerful component of a multiple biomarker strategy in managing HF patients.
Abstract : The purpose of this study was to determine the management of the learning process during a pandemic in Islamic boarding schools including management principles such as planning, organizing and evaluating by including various factors in it in order to achieve the expected learning objectives. This is necessary considering that until now educational institutions that still carry out face-to-face learning can be said to be only Islamic boarding schools. The object of this research is Modern Pondok Daarul Hikmah Tangerang – Banten. The method used is qualitative data obtained through observations and structured interviews with the management team of Islamic boarding schools. From several observation items and interview results, it can be concluded that Islamic boarding school learning is carried out offline (face to face) through management principles with health protocols . First, learning planning still refers to educational goals and applicable Islamic boarding school values. Both learning organizations are carried out based on the structure and main tasks of each element such as teachers, students and employees. Third, from the control aspect, in this case the learning evaluation is carried out objectively and adaptively, namely adjusting several aspects to government regulations and internally applicable regulations.