About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ2810215510399
Sapporo Medical Journal
Author : Sudiyati, Asri C Adisasmita, Hadi Pratomo, Rini Sekartini,

Abstract : Monitoring the development of early childhood (Early Child Development) is a very important thing that must be done in every country. To carry out such monitoring, an instrument that is easy, low-cost but valid and reliable is needed in assessing child development. Instrument development efforts have been carried out in various countries, both developing new instruments and adapting existing instruments. The purpose of this research isidentify steps in developing instruments for measuring child development in various countries that are easy to implement but valid and reliable. literature review through the article search stage from data-based online, English-language articles published from 2010-2020, which contain research content on the development of child development measurement instruments. Of the 17 articles reviewed in developing instruments, 3 articles on creating new instruments, 10 adapting existing instruments, and 4 only testing and comparing with gold standard instruments. All articles go through the validity and reliability test phase. However, only 8 used other instruments as the gold standard

Paper ID : SMJ2810215510398
Sapporo Medical Journal
Author : Ariuntstetseg Altanbat, Selenge Erdenechimeg, Tserendulam Luvsandorj, Ulambayar Lkhamsuren,

Abstract : Abstract-- Recently, herbal supplements have been widely used to treat upper respiratory illnesses, colds, and sore throats. Lozenges are one of the most widely used forms of medicine. The dosage form is prepared to have a pleasant taste and has a large number of advantages in the pharmaceutical market. The lozenge has a direct effect on the oral mucosa, has partial and general action, increases bioavailability, reduces gastric irritation, does not pass through the liver, does not need to be swallowed, and has many advantages such as ease of use and ease of production and storage. Currently, only herbal medicines such as Koflet, Koflet-N and Dr. Mom, which are used for the needs of the population of Mongolia, are imported. Therefore, there is a need to study the possibility and output of import-substituting products at home. We use Glycyrrhiza uralensis Fish, Eugenia caryophyllata Thunb, and Kaempferia galangal, which are widely used in Mongolian traditional and modern medicine to clear phlegm, relieve cough, heal wounds, and relieve pneumonia. The goal is to develop a technological scheme for drug preparation. We developed a technological scheme for lozenge containing liquorice. Some criteria for lozenges quality: appearance, base quality, solubility, average weight (n = 5) M = 2.5 ± 0.02, weight variation (± 4%), strength (n = 5) M = 99.2 ± 0.01, the moisture content (n = 5) was found to be M = 0.18 ± 0.01 p <0.05.

Paper ID : SMJ2510215510397
Sapporo Medical Journal
Author : Dang Xuan Cuong, Do Thi Hong Tuoi, Le Tran Trong Khoi, Pham Duc Thinh, Nguyen Ngoc Bao Huy, Dang Thi Thanh Tuyen, Nguyen Thi Kim Oanh, Nguyen Le Thanh Tuyen, Pham Thanh Thuan, Nguyen Thi My Le, Vuong Van May, Nguyen Thi Thang Long, Hoang Duc An, Hoang Thai Ha,

Abstract : The characteristics evaluation of the physic (sensory, swelling, disintegration, active ingredient release, bulk density, and mass uniformity), biochemistry, acute toxicity, and accelerated aging of polyphenol/chlorophyll pillulae was presented in the current study. Pillulae contained the polyphenol/chlorophyll-rich concentrated extract of corn by-products in Khanh Hoa province, Vietnam. The biochemistry characteristics were analysed, such as the content of polyphenol, chlorophyll, ascorbic acid, thiamin, tocopherol acetate, alginate content, and Ca2+, bioactivities (total antioxidant activity, reducing power activity, DPPH free radical scavenging activity, catalase activity, formation inhibition of conjugated dienes, low-density lipoprotein-antioxidant activity). Pillulae was tested for acute toxicity and accelerated aging for 30 days at 60oC and checked micro-organism. The results showed that pillulae was non-toxic with a maximum dose of 75 pillulae/kg. The sensory, swelling and active ingredient release of pillulae was good with bulk density (0.6 g/cm3), and mass uniformity (140.12 mg) and polyphenol (31.95 mg), chlorophyll (110.02 µg), ascorbic acid (20.27 mg), thiamin (0.22 mg), tocopherol acetate (1.2 mg), alginate content (20.46 mg), and Ca2+ (12 mg). The storage time of pillulae was estimated to be one year at 25oC through accelerated aging storage for 30 days at 60oC, and only detection of total aerobic bacterial (2.8x102 CFU/g) on the 30th day of accelerated aging.

Paper ID : SMJ2010215510396

Abstract : The focus of the study was to evaluate the effect of the bootstrapping method on an applied sciences study. In this case study, a set of data from the design of an experiment (DOE) was taken which consisted of 20 observations, which is specifically design for Two-way Analysis of Variance (ANOVA). After reorganizing the data according to the specific template, a regression approach to one-factor Analysis of variance was used for the best model fitting which considering all the factor levels. At first, the regression was fit through the origin data. Second, the bootstrapped method was applied towards the origin data through SAS syntax in order to obtained large sample data, then the obtained data was used for regression fitting. The regression results with and without bootstrap was compared according to the parameter of estimated coefficient beta, standard error and the obtained p-value. To validate the obtained model, a multilayer perceptron neural network was applied, the Mean Error (ME), Mean Absolute Error (MAE) and Maximum Error were compared towards training, testing and validation procedure. As a conclusion, the regression approach through bootstrapping to one-factor Analysis of variance was a significant methodology. The mean error (ME) and mean absolute error (MAE) of the measurement of the model accuracy are relatively similar to the training, testing, and validation. Small error measurement was showing the high accuracy of the developed model. Hence, it can be conclu

Paper ID : SMJ1910215510395
Sapporo Medical Journal
Author : Ahmad A. Alsolmi, Mohannad A. Al-Zahrani, Abdulrahman M. Banasser, Marwan A. Bader, Naif A. Al-Ansari, Omar A. Al-Sulami, Abdulrahman J. Sabbagh,

Abstract : Smartphone addiction may be considered one of the most prevalent habits in Saudi Arabia, with users ranging between 41 and 44 million. This addiction has a debilitating impact, including increase in headaches. We aim to determine the relationship between smartphone addiction and headaches among medical students at King Abdulaziz University, Jeddah, Saudi Arabia. This cross-sectional study involved 429 medical students of the faculty of Medicine at King Abdulaziz University. Data were collected by an electronic self-reported questionnaire containing demographic questions and scales for smartphone addiction (SAS-SV), headache impact on participants’ lives (HIT-6), and headache assessment questions. Data were entered into Microsoft Excel and analyzed using SPSS version 21. Pearson’s chi-square was used to determine the significance of the relationships. The results showed that more than half of the participants were addicted to using smartphones. Statistical analysis found no significant relation between smartphone addiction and headache frequency throughout students’ lives. However, there is a significant relationship between headache impact and addiction. Furthermore, there is also a significant relationship between avoidance of activities and addiction. Smartphone addiction negatively affects medical students by increasing the impact of headaches on their lives, which is worse than addiction by nature. An alternative for the excessive use of smartphones should be introduced.