Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : Objective: This study aims to evaluate the value of using mediastinoscopy in the diagnosis and treating of mediastinal lesions in lung cancer.Lung cancer is known to be the leading cause of cancer mortality globally, and it is also ranked first on the prevalence of cancer against the planet’s population. Materials and methods: the study was performed by mediastinoscopy on 106 patients to diagnose lung cancer. We have used general clinical, laboratory, endoscopic (EBUS-TBNA, CMM), radiographical (CT, PET-CT), morphological, immunohistochemical, and statistical methods of study. For applied mathematics analysis results, we used Statistica for Windows Version 10.0 (Stat Soft INC., USA). Parameters are given within the form M±m, where M is the mean, m is the standard deviation. In the case of p<0.05, variations were set as statistically vital. Results: The number of patients in the study (who performed mediastinoscopy 106, 65 were represented by lung cancer). Conclusion: Mediastinoscopy remains the most effective diagnostic investigation of choice for paratracheal and retrovascularmediastinal pathology, especially in lung cancer.
Abstract : Surgery in scoliosis patients can affect postoperative quality of life, especially in adolescents (AIS). Early detection of AIS and proper management are the keys to a satisfactory outcome. This study aims to assess the clinical condition or quality of life of postoperative patients and improvement of the Cobb angle degree in AIS patients at Dr. Soetomo Hospital. This research is a cross-sectional study. Patient data obtained from medical records include age, gender, and year of operation. Radiological data obtained by measuring the difference in Cobb angle pre and postoperatively. Clinical outcome data were obtained from the SRS (Scoliosis Research Society) Questionnaire Version 30. There were 22 patients in this study, consisting of 17 female patients (77.2%) and 5 male patients (22.8%). The average value of the correction angle of the Cobb angle is (30.73o + 15.25o). Based on the results of the calculation of the SRS-30 questionnaire, the mean function value is 3.94+0.24, the mean pain value is 3.96+0.42, the mean self-image value is 3.29+0.27, the average mental health value is 3.37+0.49, and the average value of the level of satisfaction with operating result is 3.28+0.28. From this research, found a positive effect on aspects of postoperative quality of life in AIS patients.
Abstract : The Citarum River is the longest river in West Java stretching from Bandung City to the Jakarta bay. This river has been utilized as a vital object to provide power generation, irrigation, drinking water, and household utilities. The existence of heavy metals such as mercury (hg), cadmium (Cd), & Lead (Pb) in the river has become a serious concern. This research was aimed to analyze human health risk exposed by heavy metals from the consumption of the water, fish, and vegetables around the upper Citarum River. River water, well water, fish, & vegetables were collected around The Citarum River to analyze heavy metals content (Hg, Cd, and Pb). In this research, the concentration of Cd in all samples were below the standard limit. The concentration of Hg in fish & vegetables samples ranged from 0.17 – 0.78 mg/kg and <0.02 – 0.042 mg/kg, respectively. Meanwhile, Hg concentration was below the limit of detection for river and well water. Pb concentration in river, well water and vegetables were below 0.005 mg/l & below 0.1 mg/kg, respectively. Pb concentration in fish samples ranged from < 0.1 – 0.28 mg/kg. In this result, we found that fish sample D had the highest concentration for all heavy metals than other samples. It was estimated that fish samples around the upper Citarum River were not safe for consumption based on Hg tolerable daily intake with risk question (RQ) value was over than 1. However, it was still tolerable for Cd and Pb.
Abstract : Osteoarthritis is the single most common cause of disability in older adults. A study reported that musculoskeletal disorders were much greater than previously thought and accounted for 6.8% of the factors contributing to decreased age productivity in patients worldwide. This study is a retrospective analytic observational study with a cross sectional approach to postoperative high tibial osteotomy (HTO) patients at Dr. Soetomo general hospital and Husada Utama hospital in Surabaya. It was found that the most gender data were women with 20 patients (86.9), the most age was 51-60 years with 12 patients (52.1%), the most BMI was obese with 11 patients (61.1%), and the KOOS score of the pain, symptoms, activity daily living, sports, and quality of life components are 89.29, 92.51, 93.61, 56.96, and 82.61. Based on the FTA angle, the most patients were varus 4 and valgus 6. In addition, there were a significant difference between the mean FTA angle and between VAS average before and after surgery (p=0.000) and (p=0.000). There is an improvement in terms of clinical, radiological, and satisfactory KOOS score
Abstract : Background: Polycystic ovary syndrome (PCOS) is the commonest endocrine disorder in women of reproductive age with a prevalence of up to 10%. Aim: The aim of this study was to evaluate vitamin D levels in PCOS women compared to normal fertile women and the relation between vitamin D and fasting insulin hormone levels in PCOS women. Materials and Methods: A prospective case-control study was conducted on 80 subjects who were classified into two groups: group (I) cases included 40 infertile women diagnosed with PCOS and group (II) control included 40 normal fertile women. Demographic and clinical characteristics of all the patients were recorded Results: No significant differences were noticed between groups regarding age, body mass index, sun exposure, however, cases group had lower gravidity. The results showed that LH level was significantly higher in PCOS group compared to the control one, while the opposite trend was observed in FSH levels. The fasting insulin hormone level was higher in PCOS group compared to control. PCOS group had a significantly lower 25 (OH) D level in comparison with the control group. In the PCOS group, 25 (OH) D level was negatively correlated with both fasting insulin level and body mass index. Conclusion: Women with PCOS had a significantly lower serum 25 (OH) D level compared to normal fertile women. Insulin resistance was prevalent in PCOS patients and there was a significant inverse correlation between vitamin D level and both fasting ins