Sapporo Medical Journal

Abstract : Purpose: The aim of this study was to assess the ability of topical use of autologous platelet rich plasma (PRP) to improve success rate of myringoplasty. Patients and Methods: This investigation was led to the ENT Department at Minia University Hospital and included 30 patients with different sizes, dry, central tympanic membrane perforation, attending the E.N.T. outpatient clinic. Half the patients underwent fat graft myringoplasty (group A), while others received the fat graft with PRP (group B). Results: The graft was taken in 13 patients (86.7%) in group A, and in 14 patients (93.3%) in group B. Healing time was shorter in group B (2 months) than in group A (3 months). There was insignificant different between the two graft types in hearing gain, but in each graft type there was significant decrease in the mean ABG postoperatively. Conclusion: Effective autologous PRP application during myringoplasty has favorable healing results in small, medium sized and large central perforations

Abstract : Introduction: Stroke is one of the leading causes of morbidity and mortality worldwide. Hypertension, diabetes, dyslipidemia, obesity, smoking and lack of physical activity are all modifiable risk factors that can prevent stroke. BE-FAST, an acronym for balance, eyes, face, arm, speech and time, can be used to recognize more than 95% of ischemic strokes. Objective: This study aims to assess the general knowledge of university students in Saudi Arabia regarding the common symptoms of stroke as well as their awareness of when to present to a medical facility. Methodology: A cross-sectional study conducted as an online survey distributed amongst university students from King Abdulaziz University in Jeddah, Saudi Arabia from September-October 2020.Statistical analysis was done using IBM SPSS Statistics Version 20. Results: A total of 321 volunteers participated in the study. Facial asymmetry and hemibody weakness were the least symptoms to be recognized among the studied sample (29% and 40.8% respectively). The awareness of the urgency to seek medical help was very high as 90.7% said that they need to seek medical help as soon as symptoms appear and 92% said that they would go to the Emergency Room rather than outpatient clinics. Conclusion: Awareness of stroke symptoms is associated with better prognosis however current knowledge of university students is still suboptimal especially regarding some of the common early symptoms/signs like facial and hemibody weakness.

Abstract : This study aimed to determine the risk factors that affected the pulmonary function disorder of workers in the manufacturing industry. The research was observational with cross-sectional design, the population were 286 workers while the total sample were 150 workers in the production unit who have worked at least five years, and willing to become respondents. Data collected from interviews with workers and measurement of environmental parameters. Bivariate analysis used Chi-Square test and multivariate test using PLS-SEM (Partial Least Square- Structural Equation Modeling). The result of the bivariate showed that there were a significant correlation between the level of inhaled dust, the use of PPE, and nutritional status (p-value < 0.05 ) with pulmonary function disorder of workers and there are no correlation between total dust levels, gender, age, smoking habits, exercise habits, medical record, temperature, humidity, ventilation, and working period (p-value > 0,05). Multivariate test results (PLS-SEM) showed result of the dust exposure factors of 20.1%, physical environment of 11%, individual factors of 18%, and behavioral factors of 15.7% on pulmonary function disorder. The variable of workers pulmonary function disorder was affected by dust exposure, physical environmental factors, individual factors, and behavioral factors to 64,8%.

Abstract : The long-term use of plastic for food packaging affects monomer migration. Bioplastics can be used as an alternative for food packaging because bioplastics can reduce risks of health. This research aimed to determine the effect of glycerol and chitosan doses for the utilization of cassava peel waste as bioplastics food packaging and its effect on physical and microbiological food quality. This research is experiment with the independent variable of glycerol and chitosan doses as (3 % weight: 3 ml, 5 % weight: 5 ml and 7 % weight: 7 ml) and the dependent variables are the physical and microbiological quality of food. Sample at this research is Getuk, with 24 samples Getuk (100 gr/sample). The result of the research is total plate count of control as 11500 CFU/g, treatment group 1 at 8783 CFU/g, treatment group 2 at 6716 CFU/g, and treatment group 3 at 4400 CFU/g. Analysis of statistics used ANOVA test, the result showed significant differences in doses of glycerol and chitosan for organic waste utilization of cassava peels as bioplastics food packaging to physical and microbiological food quality with a p-value as = 0,000. The conclusion of this research is the addition of 7 % weight chitosan and 7 ml glycerol showed the optimal treatment to reduce the total plate count of food (getuk) and the organoleptic test showed the food (getuk) packaging with bioplastics quality is better than regular plastic packaging. It’s recommended to use bioplastics as food packaging because it's

Abstract : Otorhinolaryngological manifestations are among the clinical manifestations of COVID-19 infection. It’s crucial for the general population to have a holistic view about theses manifestations as a part of controlling pandemic. This study aimed to report the results of the perception and knowledge about COVID 19-related otorhinolaryngological symptoms in Saudi Arabia. This is a cross sectional anonymous questionnaire-based study that was carried in Saudi Arabia. The questionnaire included a variety of questions to evaluate public perception and knowledge about otorhinolaryngological manifestations due to COVID-19 infection. One thousand five hundred twenty-one responded to the questionnaire. Most of the participants have identified otorhinolaryngological clinical manifestations of due to COVID-19, dyspnea (85%), hyposmoa or anosmia (82%), dry cough (78%). Study participants were willing to call ministry of health hotline(MOH) in 74.6% when experiencing otorhinolaryngological manifestations during COVID-19. In addition,70% were convenient with self-isolation. However, most of them were cautious to visit the otorhinolaryngological clinics during the pandemic era. This study showed that Saudi people have sufficient knowledge about COVID-19 otorhinolaryngological manifestations. This reflects the success of MOH guidelines to control COVID 19 infection. Nevertheless, extra campaigns with special emphasis of otorhinolaryngological illness still needs to be implanted in a wider scale.