Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:
Abstract : Abstract— Electronic Medical Record (EMR) is a document containing patient data using an electronic system. In the future, electronic medical records are not any digital paper charts, but a digital application that can actively interact with providers and patients. The amount of time for doctors to complete EMR and the presence of a computer screen in the middle of interactions between doctors and patients might cause distractions in interactions between doctors and patients. This review aims to conclude how the use of EMR affects the interaction between doctors and patients also how it may improve the quality of doctor-patient relationships in clinical settings. The method used in this study is a systematic search following the PRISMA guidelines. With 10 articles obtained, various results were found regarding the relationship between the use of EMR and the interaction between doctors and patients. Adaptation between users and the application is needed to respond to medical challenges and improve service performance. Involving patients in the use of EMR can resulting a better impact on the quality of interaction between doctors and patients which can ultimately increase satisfaction and the outcome in therapy. Further research is needed to optimize the use of EMR.
Abstract : Cigarette smoking has been associated with increases in inflammatory and oxidative stress in tear films and causes decreasing in tear film parameters value and goblet cell density. This study purposed to investigate the effect of acute cigarette smoke exposure on cytokine levels (IL-1, IL-6, and IL-8) and malondialdehyde levels in murine lacrimal gland tissue. The design was posttest-only with a control group study. Thirty-six male Wistar rats, aged three months old with weighing 250-300 grams, were included and divided into two groups, cigarette smoke exposure and the control group. The exposure to cigarette smoke was carried out thrice a day, 30 minutes each, for 21 days. On the 22nd day, the exoorbital lacrimal gland tissues were obtained to examine the concentrations of IL-1, IL-6, and IL-8 with the ELISA test and malondialdehyde levels with the TBARS assay method. The results show significantly elevated cytokines level in the cigarette smoke group, especially IL-1 and IL-8 concentration than the control group. The malondialdehyde levels also increased significant statistically in the cigarette smoke group. Increasing levels of cytokines and malondialdehyde indicate that cigarette smoke exposure promotes the inflammation process and oxidative stress in lacrimal gland tissue. The oxidative stress-induced inflammation process will damage the lacrimal gland, which causes aqueous production disturbance, and eventually causes dry eye disease.
Abstract : Alginate/lignin is an antioxidant biomaterial synthesized from alginate of brown algae and lignin of maize by-product by spray drying method. Alginate/lignin was evaluated for lignin content, alginate content, and its antioxidant activity according to the storage time, for example, storage at 25oC for 18 months and accelerated aging at 55oC for 137 days. The results showed that alginate/lignin was stable in content and antioxidant activity for 24 storage months. The significant decrease (p<0.05) in lignin content, alginate content, and antioxidant activity changed according to the linear model for the two storage methods. Alginate/lignin content decreased by under 3% after 24 storage months. Microorganisms of alginate/lignin increased according to the storage time and faster in the storage method at 25oC, compared to the accelerated aging method.
Abstract : Polysaccharides of marine algae belong to anion groups such as fucoidan and alginate are known the treating ability of gastric ulcers but carrageenan has not seen the announcement yet. Therefore, the paper focused on the treating ability evaluation of gastric ulcers of carrageenan that was extracted from Kappaphycus alverazii grown in Vietnam. Three acid agent (hydrochloric acid, 5-sulfosalicylic acid, and acetic acid) in various concentration (1, 5, and 10%) was used for causing disease. Various concentration of carrageenan (0.5, 1.0, and 1.5%) was used for the treating of gastric ulcers. Guinea pig (Cavia porcellus) was observed clinical pharmacology (rate of blood sedimentation and gastric disease surgery) on day 5th and 10th after the treatment. The results showed that carrageenan has the treatment effect of gastric ulcers. A concentration of 1.5% (w/v) carrageenan is a suitable choice for the protection of the gastric mucosa of mice that drunk 10% hydrochloric acid after a 10-day treatment. In summary, carrageen extracted from Kappaphycus alverazii grown in Vietnam can completely be used in food and pharmaceutical products, especially in the preparation of drugs, and functional foods to support the treatment of gastric ulcers.
Abstract : Introduction The 2019 coronavirus disease pandemic is reported to have an adverse psychological impact. There is paucity of data concerning the psychosocial effect of the COVID-19 pandemic on individuals with mental health diseases. Objective This study aims to investigate the psychological impact of COVID-19 among the general population compared to individuals who have been diagnosed with a mental health disease. Methods A cross-sectional study was conducted in early 2021 using a self-administered questionnaire. Respondents completed a modified and translated form of the COVID-19 Pandemic Mental Health Questionnaire (CoPaQ) that assessed the psychosocial impact of the COVID-19 pandemic. Results and Discussion A total of 287 respondents (160 males and 127 females) completed the survey. Of the 287 respondents, 74 reported having been diagnosed with a mental health disease. Nearly a quarter of respondents (24%) reported that a family member had died due to COVID-19. On the impact of the COVID-19 scale, the items were rated as extremely distressing by 10.8% to 33.4%. Female gender, low monthly income, mental health diagnosis, and a high number of risk factors for a severe COVID-19 infection negatively influenced the respondents’ rated distress scores. Conclusions The burden of mental health disease increases during an isolating time such as a pandemic. Online psychological interventions should be designed.