Sapporo Medical Journal

Abstract : Introduction: The use of CAD/CAM in the manufacture of PEEK and acetal frameworks helps to increase the accuracy and retention of the partial denture frameworks. Aim: is to compare the retentive force of peek and acetal digitally milled partial denture frameworks. Materials and Methods: Twenty digital partial denture framework were milled by CAD/CAM, divided into two equal groups (n=10), ten digitally milled PEEK frameworks and ten digitally milled acetal frameworks. Preparation the clasp of two partial denture was designed on CAD CAM software with thickness 2 mm. and designed hook at the central and bilateral at 5,6 area occlusally to pullout the cast clasps later. Instron universal testing machine model 3345 England used with tensile load at crosshead speed of 5 mm/min until automatically stopped. Results: Retentive force of PEEK was higher than retentive force of acetal in bilateral and unilateral measurement. Conclusion: PEEK should be considered as a substitute framework material for a well-designed Cr-Co RDP.

Abstract : The aim: is to evaluate antibacterial efficacy of sonically activated (Salvadora persica / Glycyrrhiza glabra Extracts) compared to sonically activated (sodium hypochlorite / EDTA) against Enterococcus Faecalis in an in-vitro model Material and methods: Sixty Human mandibular premolars were collected and a standardized tooth length of 18mm was established. Then root canals were instrumented and all samples were autoclaved. 15 specimens were then subjected to microbial analysis and served as negative control group. The remaining 45 specimens were inoculated with E faecalis suspension. 15 specimens served as Positive control group, 15 specimens served as Group (A) where sonically activated (2.5 % NaOCl / 17% EDTA) was applied and 15specimens served as Group B where sonically activated (Glycyrrhiza glabra / Salvadora persica Extracts) was applied . For all specimens were subjected for microbial analysis. Results: group A (NaOCl / EDTA) recorded the lowest median bacterial count at 0.6 log CFU while; group B (G. glabra /S. persica) showed median bacterial count of 1.2 log CFU. The results showed a statistically significant difference in comparison with positive control group p < 0.001 indicating the strong antibacterial activity of both irrigation protocols of group (A, B). Furthermore group A showed a statistically significant more reduction in bacterial count than did group B at p value < 0.001; indicating the superior antibacterial activity of group A. Conclusion: sonically

Abstract : All eukaryotic cells release nanosized extracellular vesicles, or nEV, into the extracellular spaces. They have been found in various bodily fluids and are critical as intercellular communication mediators. nEV transport proteins, lipids, metabolites, and nucleic acids from donor cells to destination cells nearby or at a distance, altering the recipient cells' biological characteristics. Because of this specific characteristic, EVs are an excellent drug carrier for medicinal purposes. Compared to manufactured nanoparticles, natural encapsulation (nEV) has several benefits, such as biocompatibility, natural targeting capability, and long-term safety. Additionally, nEV can be swiftly loaded with the preferred medication, separated from a variety of biological sources, and altered to increase their effectiveness as specific drug delivery vehicles. Here, we review these facets of nEV and discuss the factors to consider when selecting the drug loading technique, nEV source, and surface modification tactics. We also discuss the obstacles that need to be removed for nEV-based drug delivery technologies to reach their full potential in clinical settings.

Abstract : Aim: The purpose of this in vitro study is to evaluate two intraoral scanning accuracy regarding to internal fit of provisional restorations. Methodology: A maxillary acrylic cast will be used with two designs. Design 1: Acrylic resin maxillary cast will be used after removal of right canine and then block their positions with wax. the abutments are maxillary central and lateral incisor and first premolar. The abutments will be prepared using the dental milling machine and then scanned by a laboratory scanner to make a virtual model, which will be used to make ten models by 3D printing. Design 2: Acrylic resin maxillary cast, the abutments are maxillary sex anterior teeth from canine to canine. The abutments will be prepared using dental milling machine and then scanned by a laboratory scanner to make a virtual model, which will be used to make ten models by 3D printing. These ten models will be used to make single crowns using Omnicam and Prime scan. After scanning the abutments, provisional single crowns will be milled using Telio CAD blocks and adapted to the corresponding dies. Internal fit will be evaluated using a measuring microscope. Results: The results revealed that there were significant results between Primescan and Omnicam for all scanned teeth. Conclusion: The provisional restorations scanned with Primescan intra-oral scanner had better internal fit than restoration scanned with Omnicam intra-oral scanner.

Abstract : Abstract Background: Self-care practices aimed at perineal health have gained attention for their potential to bolster postpartum recovery, alleviate discomfort, and forestall enduring issues. Objective This study aimed to investigate the multifaceted dimensions of self-care practices for perineal health among Primiparous Women. Method: Employing a descriptive-analytic (cross-sectional) approach, the research involved 260 Primiparous Women at a Maternity Teaching Hospital in Sulaimani City. Data collection transpired over four consecutive months from September 2022 to March 2023 through direct interviews employing a questionnaire encompassing Maternal Demographic Characteristics and Postnatal Self-care practices. The results revealed that the postnatal self-care practice awareness was diverse: 45.4% displayed poor awareness, 44.2% exhibited fair awareness following an episiotomy, and 10.4% showcased good awareness. In conclusion, this study underscores the significance of addressing perineal health via self-care practices, given their potential for augmenting postpartum recovery, alleviating discomfort, and averting long-term complications. The research accentuates an alarming trend in postnatal self-care practice awareness, highlighting a substantial portion of participants with limited awareness. This underscores the urgency of targeted interventions and educational efforts to cultivate enhanced self-care practices among Primiparous Women, fostering better perineal health