About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ2812215512420
Sapporo Medical Journal
Author : Essam M.Abdel Aziz, Hodna A. Elmorshedy, Alaa S. Abd-Elkader, Mostafa A. Haridi,

Abstract : ESRD is a global public health issue, with rising incidence and prevalence, high costs, and poor outcomes. Diabetic nephropathy, hypertension, glomerulonephritis, interstitial nephritis, pyelonephritis, polycystic kidney disease, and obstructive nephropathy are the most common causes of CKD

Paper ID : SMJ2512215512419

Abstract : Apple leaves (Ziziphus mauritiana Lam) are a traditional plant, contain numerous bioactive ingredients. The paper focused on polyphenol content and antibacterial activity of acetone, hexane, and ethyl acetate extracts from apple leave Ziziphus mauritiana Lam selecting in Ninh Thuan province, Vietnam on four-strain Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococus aureus. Antibacterial activity of different fractions was evaluated by using minimum inhibitory concentration. The results showed that apple leaves (Ziziphus mauritiana Lam) exhibited high antibacterial activity as the evaluation of antibacterial activity by using MIC method in liquid medium, and MIC of three fractions was in the range of 3.125 to 6.25 mg/ml. Polyphenol content of acetone fraction from apple leaves was 68.96 ± 0.53 mg gallic acid equivalent/g DW. The purity of polyphenols in different fractions was arranged in ascending order, acetone, n-hexane, and ethyl acetate. Apple leaves Ziziphus mauritiana was potential in functional food and pharmaceuticals.

Paper ID : SMJ1712215512418
Sapporo Medical Journal
Author : Rafal N. Balubaid, Hassan M. Masmali, Rufaydah S. Alsabbah, Wedad T. Hawsawi, Amna A. Bahareth, Hanan Alkaabi, Sally Farhat, Ahmed H. Abouissa,

Abstract : This case series investigated the outcomes of children who received the maximum tolerated dose of hydroxyurea for sickle cell patients with avascular necrosis of the femoral head (AVNFH) at Maternity and Children Hospital, Makkah, Kingdom of Saudi Arabia (KSA) over one year. This retrospective case series report describes four pediatric patients under the age of 14 with sickle cell disease complicated by AVNFH. We excluded all patients who were non-compliant to medication, missed follow-up, started on another modality of treatment, or did not complete laboratory work-up or imaging. Patients were started on the maximum tolerated dose of hydroxyurea, and the assessment was conducted according to clinical manifestations and radiological findings. Our study found significant clinical and radiological improvement in sickle cell patients with AVNFH who took the maximum tolerated dose of hydroxyurea.

Paper ID : SMJ0912215512415
Sapporo Medical Journal
Author : Amien Suharti, Physiatrist (PM&R doctor), Evi Rachmawati Nur Hidayati, PhD, Physiatrist (PM&R doctor), Hafizia Asri Yusviani, MD, Savira Widha Alifprilia, MD, Zuliza Adha, MD,

Abstract : Measuring chest expansion is considered to perform in COVID-19 patient to assess the pulmonary function impairment as its usage to other interstitial lung diseases. The decrease of pulmonary function will affect the cardiorespiratory functional capacity. These problems demand an appropriate pulmonary rehabilitation programme aimed to returning the decent quality of life. Among 43 subjects we prescribed two types of breathing exercise: incentive spirometry and diaphragm breathing exercise. The chest expansion at three levels (axillary, nipple, and xiphisternum) was measured before and after breathing exercise; then average of its improvement was recorded. The assessment of functional capacity using 4-meter gait time test (4MGT) was also performed after sequence of breathing exercises. This study showed improvement of chest expansion on majority of subjects. Based on bivariate analysis using Spearman correlation, the p value was 0,012 (p <0,05) and coefficient correlation was 0,381. We can conclude that there was correlation between chest expansion improvement and functional capacity measured by 4MGT after breathing exercise in COVID-19 patient.

Paper ID : SMJ0612215512414
Sapporo Medical Journal
Author : See Heng Jee, Muhammad Hafiz Hanafi, Muzaimi Mustapha, Nur Karyatee Kassim, Kamarul Imran Musa,

Abstract : Hemorrhagic stroke is a highly debilitating condition with several rehabilitation problems.This study aimed to discern the effects of intensive TENS therapy for 2 weeks, on a motor-impaired haemorrhagic stroke patient’s recovery, with 6 weeks of conventional physiotherapy, to elucidate the effect of TENS and conventional physiotherapy on serum Creatine Kinase and serum Troponin T. Our outcome measures were serum Creatine Kinase, serum Troponin T, and modified Barthel Index scores. This was a pre-post convenient sampling controlled interventional study, conducted in Hospital Universiti Sains Malaysia, with 10 control subjects and 10 TENS-therapy subjects. The intervention group underwent intensive TENS therapy and conventional physiotherapy for 2 weeks, then 4 weeks of conventional physiotherapy. The control group underwent 6 weeks of conventional physiotherapy. All three outcome measures were measured before and after 2 weeks of intensive TENS therapy and 6 weeks of conventional therapy. Results indicated Creatine Kinase and Troponin T were unaffected by 2 weeks of intensive TENS therapy and 6 weeks of conventional physiotherapy (Creatine Kinase p=0.521) (Troponin T p=0.632). The same also applied to 6 weeks of conventional physiotherapy alone (Creatine Kinase p=0.572) (Troponin T p=0.921). Conversely, modified Barthel Index score comparisons show significant increases in intervention group (p=0.040) compared to control group. This study is a pilot study for future research.