About

Sapporo Medical Journal

Sapporo Medical Journal is an open access, monthly, peer reviewed International Medical Journal with focuses on publishes research conducted in all fields of medical, medicine. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Sapporo Medical Journal is a scopus indexed International Medical Journal that wants to publish original articles, research articles, review articles with top-level work from all areas of Medicine, General Medicine, Medical Science Research and their application including Aetiology, bioengineering, biomedicine, cardiology, chiropody etc.
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal
Sapporo Medical Journal

Sapporo Medical Journal aims to distribute and expand medical data to the World as well as build a supportive and vibrant community of researchers to connect and explore ideas by publishing articles related to all fields of medicine. Sapporo Medical Journal believes that quality and ethical research. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to:

Medicine Microbiology Biochemistry Pharmacology Pathology Forensic medicine Internal Medicine Physiology Anatomy Obstetrics and Gynecology Radiology Community Medicine Otorhinolaryngology Infectious Diseases General Surgery Cancer research Pulmonary Dermatology and Venereal diseases Orthopedics Neurology Anaesthesia Medical education Infectious Diseases and Vaccinology Neurosurgery Gastroenterology Nephrology Paediatrics Reproduction Dental Cardiology Surgery Nursing Otolaryngology Dermatology Diabetes Orthopaedics Hepatology Urology Psychology Anesthesiology Endocrinology Biotechnology Venereology ENT Psychiatry Pharmaceutical Analysis Pharmacy Pharmaceutical Chemistry Pulmonology Pharmaceutics Pharmaceutical Pharmacognosy Biopharmaceutics Phatmaceutical Technology Quality Assurance Pharmacodynamics Pharmacokinetics Drug Regulatory Industrial Pharmacy Pharmaceutical Nanotechnology Drug Design Affairs Phytochemistry Drug Delivery Systems Drug Discovery Pharmaceutical Microbiology Pharmacy Practice Hospital Pharmacy Clinical Pharmacy Pharmacogenomics Drug Metabolism Pharmacovigilance Toxicology Clinical Research Microbiology Phrmacoinformatics Life Sciences like Chemistry Epidemiology Biomedical Sciences Immunology Dentistry Oncology Biomedicine Physiotherapy Sexology Neuroscience Gynaecology Dermatoepidemiology Pharmacy and Nursing Angiology/Vascular Medicine Osteology Ophthalmology Haematology Kinesiology Critical care Medicine Pharmacognosy and Phytochemistry Clinical immunology Bariatrics Genomics and Proteomics Clinical and Hospital Pharmacy Radiobiology Cell Biology Geriatric Medicine Healthcare Services Healthcare Management Bioinformatics and Biotechnology
Paper ID : SMJ0307215507306

Abstract : Introduction, Ureterolithiasis is the most common type of all urolithiasis. The management characteristics and efficacy of ureterolithiasis management using URS, ESWL, and ureterolithotomy in Dr. Soetomo General Hospital Surabaya are evaluated in this study. Material and Method This study used a descriptive study with a retrospective design. All medical record data of patients with reteral stone who were treated at Dr. Soetomo General Hospital Surabaya from 2014-2019. Result There were 801 patients included in the study. The highest incidence of ureteral stones was in the 51-60 years old age group (31.08%), predominantly among male patients (67.79%). URS was the most commonly performed procedure (61%). There were 270 patients with stone size < 1 cm. The procedures performed were URS and ESWL. The URS group showed significantly higher postoperative treatment (3.4 ± 2.1 days) compared to the ESWL group (p<0.05). There were 531 patients with stone size > 1 cm. The procedures performed in this group were URS, ESWL, ureterolithotomy. The shortest mean operation duration was in the ESWL group (61.56 minutes, p<0.05). Conclusion, The highest stone-free-rate (SFR) was discovered in the ureterolithotomy group (97.1%, p<0.05). ESWL had the shortest postoperative treatment duration (1 day, p<0.05). Ureterolithotomy generated the highest SFR. However, the patients had a greater hb change compared to URS. Keywords— Ureteral stone, URS, ESWL, Ureterolithotomy, Stone-free rate

Paper ID : SMJ2006215506304

Abstract : This was a descriptive study with a retrospective approach evaluating the medical record data of renal trauma patients for the past four years. A total of 84 renal trauma cases were obtained, consisting mostly of 5 to 20 years old (35.71%) male (86.9%) patients. The types were classified into blunt trauma (95.2%) mostly caused by motor vehicular accidents and penetrating trauma (4.8%). The severity was mostly dominated by grade I trauma (33.3%) followed by grade IV (23%) and III (19,2%). Anemia was the most prevalent complication (28.3%) and most patients had hematuria (82.1%). Most of the patients’ hemodynamic status was stable (86.9%) and were treated conservatively (88.4%). Only 9 patients were surgically treated with a total of 11 procedures. The most common procedure performed was nephrectomy (36.3%); followed by renorraphy (27.7%), DJ stent insertion (9%), blood clot evacuation (9%), embolization (9%), and urinoma drainage (9%). The highest mortality rate was seen among patients with grade IV renal trauma (50%). Renal trauma in East Java was mostly found in men and was caused by MVA. Most hemodynamically stable patients were mostly treated conservatively and did not require a blood transfusion. Other co-existing organ injuries affected the patients’ prognosis.

Paper ID : SMJ1906215506303

Abstract : Objective: Endothelial dysfunction (ED) in type-2 diabetes mellitus (DM) plays a crucial role in angiopathies development and progression. The most frequent cause of endothelial dysfunction in DM is oxidative stress. Aim of the study: To investigate the relationship between ascorbic acid level in serum and some anti-oxidant parameters in blood with clinical, and duplex findings of brachial artery and aorta in patients with type 2 -DM. Patients and methods: Case-Control prospective study included sixty patients with type 2-DM, and 20 healthy volunteers were included. History of peripheral ischemia, diabetic retinopathy, frequency of metabolic syndrome was analyzed. Measurements of plasma levels of ascorbate, super oxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GTx) and lipid peroxidase (LPO) were studied. Estimation of HOMA-IR was also done. Duplex study in brachial artery and aorta to measure flow mediated vasodilatation (FMD) reactive hyperemia and intima media thickness (IMT) of aorta was done. Echocardiography was done to measure ejection fraction (EF%) and left ventricular dimensions. Results: Patients’ group showed highly significantly decreased plasma insulin (P=0.009), plasma ascorbate, SOD, CAT and glutathione (P=0.001, each) than control, while showed highly significant increased plasma level of fasting sugar, T-Cholesterol, LDL and lipid peroxidation (P=0.001 each) than control. Urinary ACR was highly significantly also increased in patient’ group (P

Paper ID : SMJ1706215506302
Sapporo Medical Journal
Author : Ali Hassan Mohammed, Araz Yousif, Samir Anwar Jabbar,

Abstract : Background: Since the egression of the coronavirus 2019 (COVID-19) disease, more than 200 countries and areas around the world were affected. To the present, it is not clear whether COVID has effects on thyroid function or not. Object: The target of the current revision is to compare thyroid function in COVID cases with and without history of thyroid illness to find out the thyroid disturbance in both groups. Methods: The present study enrolled 86 COVID affected patients that alienated to groups with and without history of thyroid cases, beside comorbidities with diabetes or hypertension. Thyroid hormones [triiodothyronine (T3) and thyroxine (T4)], thyrotropin (TSH) and thyroid peroxidase (TPO) concentrations were analyzed and assessed. Results: Most of the participants (88.4%) had normal T3 and TPO level, that there was no significant difference (p = 0.069) between groups of with and without history of thyroid disease and/or upraised of TPO antibody level. Also T4 levels of the participants with no history of thyroid disease and normal TPO did not differ significantly (p =0.725) from those with a history of thyroid disease and/or high TPO. Regarding the level of TSH was significant difference (p<0.001) between the patients with high TSH, no history of thyroid disease and normal TPO (0.0%) and those with high TSH, history of thyroid disease and/or high TPO (34.0%). Conclusions: There is high prevalence of subclinical hypothyroidism in the COVID patients with family history of

Paper ID : SMJ1606215506301
Sapporo Medical Journal
Author : Firmantya Hadi Pranata, Wahjoe Djatisoesanto, Doddy Moesbadianto Soebadi,

Abstract : Prostate cancer patients often suffer castration-resistant prostate cancer (CRPC), resulting in high mortality rates. Few is still known regarding the factors affecting survival in CRPC patients. We aimed to evaluate PSA level and time to PSA nadir as a prognostic marker for survival in CRPC patients. This is an analytical retrospective study evaluating castration-resistant prostate cancer patients’ survival. Evaluated data included sex, age, initial PSA level, final PSA level, time to PSA nadir (TTN), time to CRPC progression (TTC), and survival status. There were 24 patients with CRPC included in this study. There is a significant difference (p<0.05) of initial PSA level between surviving patients (445,7 + 165,6 ng/mL) and patients who died (200.7 + 144.9 ng/mL). The association between TTN and TTC was also significant (R=0.737, p<0.05). The differences of PSA nadir level, TTN, and TTC between the groups were insignificant (p>0.05). There is a significant difference of initial PSA between surviving and non-surviving patients, whereas no notable differences are apparent in PSA nadir level, time to PSA nadir, and time to CRPC progression. However, there is an association between the time to PSA nadir and CRPC progression.